Hirkane Prerna S, Verma Umesh P, Verma Ajay K, Singh Pooja
Periodontology, King George's Medical University, Lucknow, IND.
Respiratory Medicine, King George's Medical University, Lucknow, IND.
Cureus. 2024 Jan 29;16(1):e53157. doi: 10.7759/cureus.53157. eCollection 2024 Jan.
The objective of this systematic review is to determine the association between interstitial lung diseases and chronic periodontitis from various aspects such as microbial, biomarker, genetic, and environmental levels. A systematic review was carried out from 2000 to 2021 following Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) recommendations including studies searched in PubMed-Medline, Google Scholar, and Cochrane databases. A total of more than 100 articles were obtained in the initial screening process. Out of these 42 studies fulfilled the inclusion criteria and were included in the study. According to the extracted data, there is mounting evidence suggesting the association between these two diseases. Our systematic review raises the prospect of a connection between chronic periodontitis and interstitial lung diseases, within the limitations of the studies we included.
本系统评价的目的是从微生物、生物标志物、遗传和环境水平等多个方面确定间质性肺疾病与慢性牙周炎之间的关联。按照系统评价和Meta分析的首选报告项目（PRISMA）建议，于2000年至2021年进行了一项系统评价，包括在PubMed-Medline、谷歌学术和Cochrane数据库中检索的研究。在初步筛选过程中总共获得了100多篇文章。其中42项研究符合纳入标准并被纳入本研究。根据提取的数据，越来越多的证据表明这两种疾病之间存在关联。在我们纳入研究的局限性范围内，我们的系统评价提出了慢性牙周炎与间质性肺疾病之间存在联系的可能性。
