McPheron Benjamin D, Schiano Jeffrey L, Litvak Ilya M, Brey William W
School of Science and Engineering Anderson University, Anderson, Indiana 46012.
School of Electrical Engineering and Computer Science The Pennsylvania State University, University Park, PA 16802.
Proc IEEE Conf Decis Control. 2021 Dec;2021:611-616. doi: 10.1109/cdc45484.2021.9683312. Epub 2022 Feb 1.
High magnetic fields significantly improve the resolution and sensitivity of nuclear magnetic resonance (NMR) spectroscopy measurements, which presents exciting research opportunities in areas of chemistry, biology, and material science. Powered magnets can provide much higher magnetic fields than persistent mode superconducting magnets but suffer from temporal magnetic field fluctuations due to power supply ripple and variations in cooling water temperature and flow rate which make powered magnets non-viable for high resolution NMR experiments. Previous work has demonstrated that a multi-rate sampled data cascade control system may be used to improve the resolution of NMR experiments in powered magnets. Despite these advances in reducing temporal magnetic field fluctuations, the field regulation design does not accommodate the use of pulsed field gradients, which are necessary in many NMR experiments. This work presents a control topology which accommodates the use of pulsed field gradient signals with the field regulation system. This control approach is verified using NMR measurements.
强磁场显著提高了核磁共振(NMR)光谱测量的分辨率和灵敏度,这在化学、生物学和材料科学领域带来了令人兴奋的研究机会。动力磁体能够提供比持续模式超导磁体更高的磁场,但由于电源纹波以及冷却水温度和流速的变化,会出现时间磁场波动,这使得动力磁体无法用于高分辨率NMR实验。先前的工作表明,多速率采样数据级联控制系统可用于提高动力磁体中NMR实验的分辨率。尽管在减少时间磁场波动方面取得了这些进展,但场调节设计并未考虑脉冲场梯度的使用,而脉冲场梯度在许多NMR实验中是必不可少的。这项工作提出了一种控制拓扑结构,该结构可将脉冲场梯度信号与场调节系统结合使用。这种控制方法通过NMR测量得到了验证。