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一种难以捉摸的前列腺肿瘤:表现为影像学与组织学不一致的转移性微囊性筛状癌

An elusive prostate tumour: Metastatic microcystic cribriform carcinoma presenting with imaging-histologic discordance.

作者信息

Loh Chun Khai, Chui Juanita Noeline, Zhuo Kevin Yinkit, Canagasingham Ashan, Guminski Alexander, Delprado Warick, Eade Thomas, Winter Matthew

机构信息

Department of Urology, Royal North Shore Hospital, Sydney, NSW, Australia.

North Shore Urology Research Group, Sydney, NSW, Australia.

出版信息

Urol Case Rep. 2024 Feb 11;53:102676. doi: 10.1016/j.eucr.2024.102676. eCollection 2024 Mar.

DOI:10.1016/j.eucr.2024.102676
PMID:38420334
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10900826/
Abstract

Microcystic adenocarcinoma is an uncommon histologic variant of prostate carcinoma. Despite its rarity, it has gained increasing recognition over the past decade for its diagnostic challenges and unclear prognostic significance. Herein, we describe a rare case of metastatic microcystic prostate adenocarcinoma, presenting with discordance between imaging and histologic findings. This report highlights the diagnostic and therapeutic challenges of this pathological entity and the importance of multidisciplinary collaboration in the management of intermediate-risk prostate cancer.

摘要

微囊性腺癌是前列腺癌一种罕见的组织学变异类型。尽管其罕见,但在过去十年中,因其诊断挑战和预后意义不明确而越来越受到关注。在此,我们描述了一例罕见的转移性微囊性前列腺腺癌病例,其影像学表现与组织学结果不一致。本报告强调了这种病理实体的诊断和治疗挑战,以及多学科协作在中危前列腺癌管理中的重要性。

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An elusive prostate tumour: Metastatic microcystic cribriform carcinoma presenting with imaging-histologic discordance.一种难以捉摸的前列腺肿瘤:表现为影像学与组织学不一致的转移性微囊性筛状癌
Urol Case Rep. 2024 Feb 11;53:102676. doi: 10.1016/j.eucr.2024.102676. eCollection 2024 Mar.
2
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本文引用的文献

1
Comparing the Diagnostic Performance of Multiparametric Prostate MRI Versus 68Ga-PSMA PET-CT in the Evaluation Lymph Node Involvement and Extraprostatic Extension.比较多参数前列腺MRI与68Ga-PSMA PET-CT在评估淋巴结受累及前列腺外侵犯方面的诊断性能。
Acad Radiol. 2022 May;29(5):698-704. doi: 10.1016/j.acra.2020.07.011. Epub 2020 Aug 4.
2
Prostate-specific membrane antigen PET-CT in patients with high-risk prostate cancer before curative-intent surgery or radiotherapy (proPSMA): a prospective, randomised, multicentre study.高风险前列腺癌患者在接受根治性手术或放疗前的前列腺特异性膜抗原 PET-CT(proPSMA):一项前瞻性、随机、多中心研究。
Lancet. 2020 Apr 11;395(10231):1208-1216. doi: 10.1016/S0140-6736(20)30314-7. Epub 2020 Mar 22.
3
Can Extraprostatic Extension Be Predicted by Tumor-Capsule Contact Length in Prostate Cancer? Relationship With International Society of Urological Pathology Grade Groups.前列腺癌中外囊接触长度能否预测肿瘤外侵犯?与国际泌尿病理学会分级分组的关系。
AJR Am J Roentgenol. 2020 Mar;214(3):588-596. doi: 10.2214/AJR.19.21828. Epub 2019 Oct 31.
4
Combination of Ga-PSMA PET/CT and Multiparametric MRI Improves the Detection of Clinically Significant Prostate Cancer: A Lesion-by-Lesion Analysis.镓-PSMA PET/CT 与多参数 MRI 的联合应用提高了临床显著前列腺癌的检出率:基于病灶的分析。
J Nucl Med. 2019 Jul;60(7):944-949. doi: 10.2967/jnumed.118.221010. Epub 2018 Dec 14.
5
The 2016 WHO Classification of Tumours of the Urinary System and Male Genital Organs-Part B: Prostate and Bladder Tumours.《2016 年世界卫生组织泌尿系统及男性生殖器官肿瘤分类-第 B 部分:前列腺和膀胱肿瘤》。
Eur Urol. 2016 Jul;70(1):106-119. doi: 10.1016/j.eururo.2016.02.028. Epub 2016 Mar 17.
6
Microcystic adenocarcinoma of the prostate: a variant of pseudohyperplastic and atrophic patterns.前列腺微囊性腺癌:一种假增生和萎缩模式的变体。
Am J Surg Pathol. 2010 Apr;34(4):556-61. doi: 10.1097/PAS.0b013e3181d2a549.
7
Preoperative MR imaging in the evaluation of seminal vesicle invasion in prostate cancer: pattern analysis of seminal vesicle lesions.术前磁共振成像在评估前列腺癌精囊侵犯中的应用:精囊病变的模式分析
J Magn Reson Imaging. 2008 Jul;28(1):144-50. doi: 10.1002/jmri.21422.