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布鲁氏菌病表现为罕见的单纯膝关节感染性单关节炎:一例报告。

Brucellosis an Unusual presentation as isolated septic mono-arthritis of the knee joint: A case report.

作者信息

Hassan Muad Abdi, Noor Fatima, Salehi Aram, Al Hariri Bassem

机构信息

Medical Education Department, Hamad Medical Corporation, Doha, Qatar.

Department of Medicine, Hamad Medical Corporation, Doha, Qatar.

出版信息

Heliyon. 2024 Feb 17;10(4):e26612. doi: 10.1016/j.heliyon.2024.e26612. eCollection 2024 Feb 29.

DOI:10.1016/j.heliyon.2024.e26612
PMID:38420443
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10901018/
Abstract

Brucellosis is a zoonotic infection that is widely spread across the world. It is becoming more common in Middle Eastern countries such as Qatar, Saudi Arabia, and the Mediterranean region. Despite this, we need to remain vigilant as it is still prevalent in many parts of the world. The most common presentation is musculoskeletal, but it can also present as septic arthritis in the sacroiliac, hip, or knee joints. Brucella melitensis was only found in one extended culture of synovial fluid. Treatment involved a combination of antimicrobial therapy using gentamycin, doxycycline, and rifampin. A high level of suspicion for brucellosis is necessary for any patient coming from an endemic region with non-specific and chronic arthritis to ensure early diagnosis and treatment. In this case, we present a 28-year-old male who was diagnosed with Brucellosis after developing acute septic arthritis.

摘要

布鲁氏菌病是一种人畜共患感染病,在全球广泛传播。在卡塔尔、沙特阿拉伯等中东国家以及地中海地区,这种病正变得越来越常见。尽管如此,我们仍需保持警惕,因为它在世界许多地区仍然普遍存在。最常见的表现是肌肉骨骼方面的,但也可能表现为骶髂关节、髋关节或膝关节的化脓性关节炎。仅在一份滑膜液的延长培养物中发现了羊种布鲁氏菌。治疗采用庆大霉素、强力霉素和利福平联合抗菌疗法。对于任何来自地方病流行区且患有非特异性慢性关节炎的患者,高度怀疑布鲁氏菌病对于确保早期诊断和治疗至关重要。在此病例中,我们介绍一位28岁男性,他在患上急性化脓性关节炎后被诊断为布鲁氏菌病。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/399e/10901018/7fcee7afda5e/gr3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/399e/10901018/1d30b0456ff0/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/399e/10901018/fb4b977c940a/gr2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/399e/10901018/7fcee7afda5e/gr3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/399e/10901018/1d30b0456ff0/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/399e/10901018/fb4b977c940a/gr2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/399e/10901018/7fcee7afda5e/gr3.jpg

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本文引用的文献

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Brucella Septic Arthritis: Case Reports and Review of the Literature.布鲁氏菌性败血症性关节炎:病例报告及文献综述
Case Rep Infect Dis. 2016;2016:4687840. doi: 10.1155/2016/4687840. Epub 2016 Apr 21.
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Polymerase chain reaction-based assays for the diagnosis of human brucellosis.基于聚合酶链反应的人布鲁氏菌病诊断检测方法。
Ann Clin Microbiol Antimicrob. 2014 Aug 1;13:31. doi: 10.1186/s12941-014-0031-7.
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Prematurity due to maternal brucella infection and review of the literature.母亲布鲁氏菌感染所致早产及文献综述
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A 24-year study of the epidemiology of human brucellosis in a health-care system in Eastern Saudi Arabia.沙特阿拉伯东部某医疗体系中人类布鲁氏菌病的 24 年流行病学研究。
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Treatment of human brucellosis: systematic review and meta-analysis of randomised controlled trials.人类布鲁氏菌病的治疗:随机对照试验的系统评价与荟萃分析
BMJ. 2008 Mar 29;336(7646):701-4. doi: 10.1136/bmj.39497.500903.25. Epub 2008 Mar 5.
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The new global map of human brucellosis.人类布鲁氏菌病的新全球地图。
Lancet Infect Dis. 2006 Feb;6(2):91-9. doi: 10.1016/S1473-3099(06)70382-6.
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Bacterial pathogens as biological weapons and agents of bioterrorism.作为生物武器和生物恐怖主义媒介的细菌病原体。
Am J Med Sci. 2002 Jun;323(6):299-315. doi: 10.1097/00000441-200206000-00003.
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Detection of Brucellae in blood cultures.血培养中布鲁氏菌的检测。
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