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术后和造口周围坏疽性脓皮病:坏疽性脓皮病的亚型。

Postoperative and Peristomal Pyoderma Gangrenosum: Subtypes of Pyoderma Gangrenosum.

机构信息

School of Medicine, Texas A&M University School of Medicine, 5536 Tremont Street, Dallas, TX 75214, USA.

Mohs Micrographic & Reconstructive Surgery, Epiphany Dermatology; Department of Dermatology, Baylor University Medical Center; University of Texas at Southwestern; Texas A&M University School of Medicine, 1640 FM 544, Suite 100, TX 75056, USA.

出版信息

Dermatol Clin. 2024 Apr;42(2):171-181. doi: 10.1016/j.det.2023.12.001. Epub 2023 Dec 29.

Abstract

Postoperative pyoderma gangrenosum and peristomal pyoderma gangrenosum are 2 subtypes of pyoderma gangrenosum. The diagnosis is made as a clinicopathologic correlation when assessing a rapidly progressing ulcer with irregular and undermined borders following a surgical procedure, trauma, or the creation of a stoma. Familiarity with the associated risk factors and distinguishing features of these disorders can facilitate prompt recognition, proper diagnosis, and the initiation of treatment. Management usually involves the use of corticosteroids and steroid-sparing agents as immunomodulators to shift the inflammatory neutrophilic dermatoses to chronic noninflammatory wounds and eventual healing.

摘要

术后坏疽性脓皮病和肠造口周围坏疽性脓皮病是坏疽性脓皮病的两种亚型。当评估手术后、创伤后或造口形成后迅速进展的具有不规则和边缘下凹的溃疡时,通过临床病理相关性做出诊断。熟悉这些疾病的相关危险因素和特征有助于快速识别、正确诊断和开始治疗。治疗通常包括使用皮质类固醇和类固醇节约剂作为免疫调节剂,将炎症性中性粒细胞皮肤病转变为慢性非炎症性伤口,并最终愈合。

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