Meshkin Ahmad, Badiee Fatemeh, Salari Nader, Hassanabadi Masoud, Khaleghi Ali Asghar, Mohammadi Masoud
Student Research Committee, Gerash University of Medical Sciences, Gerash, Iran.
Department of Biostatistics, School of Health, Kermanshah University of Medical Sciences, Kermanshah, Iran.
Indian J Orthop. 2024 Jan 21;58(3):223-230. doi: 10.1007/s43465-023-01089-w. eCollection 2024 Mar.
Vitamin D deficiency is widely prevalent among the elderly, posing significant health risks. This study aims to determine the global prevalence of vitamin D deficiency in the elderly.
A systematic review and meta-analysis was conducted, examining databases including Scientific Information Database (SID), Medline (PubMed), ScienceDirect, Scopus, Embase, and Google Scholar until January 2023. The publication bias of the studies was assessed using the test of heterogeneity and the Egger test.
The prevalence of vitamin D deficiency, defined as levels below 20 ng or 50 nmol was found to be 59.7% (95% CI 45.9-72.1). Furthermore, a review of six studies involving 6748 elderly individuals showed a prevalence of 27.5% (95% CI 21.8-34.1) for deficiency defined between 20 and 30 ng or 50-75 nmol. Additionally, a meta-analysis of seven studies with a sample size of 6918 elderly individuals reported a prevalence of 16% (95% CI 10.2-24.1) for deficiency defined above 30 nmol or 75 nmol.
The results of the present study reveal that the prevalence of vitamin D deficiency among the elderly is high and requires the attention of health policymakers at the World Health Organization to prioritize extensive information dissemination and screening to mitigate the adverse effects on their quality of life.
The online version contains supplementary material available at 10.1007/s43465-023-01089-w.
维生素D缺乏在老年人中广泛存在，带来重大健康风险。本研究旨在确定老年人维生素D缺乏的全球患病率。
进行了一项系统综述和荟萃分析，检索了包括科学信息数据库（SID）、医学在线数据库（Medline，即PubMed）、科学Direct、Scopus、Embase和谷歌学术等数据库，直至2023年1月。使用异质性检验和Egger检验评估研究的发表偏倚。
维生素D缺乏（定义为水平低于20 ng或50 nmol）的患病率为59.7%（95%置信区间45.9 - 72.1）。此外，对六项涉及6748名老年人的研究进行综述发现，维生素D缺乏（定义为20至30 ng或50至75 nmol之间）的患病率为27.5%（95%置信区间21.8 - 34.1）。另外，对七项样本量为6918名老年人的研究进行荟萃分析报告，维生素D缺乏（定义为高于30 nmol或75 nmol）的患病率为16%（95%置信区间10.2 - 24.1）。
本研究结果表明，老年人维生素D缺乏的患病率很高，需要世界卫生组织的卫生政策制定者予以关注，优先进行广泛的信息传播和筛查，以减轻对他们生活质量的不利影响。
在线版本包含可在10.1007/s43465 - 023 - 01089 - w获取的补充材料。
