Borriello Gianmarco, Nigro Michelangelo, D'Angiò Pierluigi, Laurino Simona, Gigliotti Andrea, Viggiano Davide, Gigliotti Giuseppe
UOC Nefrologia e Dialisi, Dipartimento di scienze mediche traslazionali, Univ. della Campania 'Luigi Vanvitelli', Napoli, Italia.
UOC Nefrologia e Dialisi, ospedale di Eboli, Salerno, Italia.
G Ital Nefrol. 2024 Feb 28;41(1):2024-vol1.
Renal involvement is very common in patients with HIV infection. The phenotype varies from the most frequently "collapsing" variant of focal and segmental glomerulosclerosis (FSGS) to "lupus-like HIV-immune complex kidney disease" (HIVICK). The latter is characterized by a histological picture that recalls lupus nephropathy. Through a clinical case, we underline the importance of urinary sediment analysis in patients with suspected glomerulopathy. Findings such as the characteristic cells that show the typical appearance of Herpes virus (HSV) infection or LE cells have significantly supported the diagnosis of HIVICK. In light of the present observations, we suggest systematically carrying out a cytological examination of the urinary sediment to confirm diagnostic hypotheses of rare pathologies.
肾脏受累在HIV感染患者中非常常见。其表型从最常见的局灶节段性肾小球硬化（FSGS）“塌陷型”变异到“狼疮样HIV免疫复合物肾病”（HIVICK）不等。后者的组织学表现类似于狼疮性肾炎。通过一个临床病例，我们强调了尿沉渣分析在疑似肾小球病患者中的重要性。诸如显示疱疹病毒（HSV）感染典型外观的特征性细胞或狼疮细胞等发现显著支持了HIVICK的诊断。根据目前的观察结果，我们建议系统地对尿沉渣进行细胞学检查，以证实罕见病理的诊断假设。
