Veraldi Stefano, Genovese Giovanni, Cerino Umberto, Nazzaro Gianluca
Dermatological Centre in Milan, Corso Venezia, 39, 20121 Milan, Italy.
Dermatology Unit, IRCCS Foundation, Ca' Granda Ospedale Maggiore Policlinico, Via Pace, 9, 20122 Milan, Italy.
Parasitol Int. 2024 Jun;100:102872. doi: 10.1016/j.parint.2024.102872. Epub 2024 Feb 28.
Follicular larva migrans (FLM) is a rare and atypical clinical presentation of hookworm-related cutaneous larva migrans (HrCLM). FLM is characterized clinically by follicular, round, small, erythematous papules that are sometimes topped by vesicles or pustules. These lesions are usually located on the abdomen, back, buttocks and thighs and are accompanied by more or less severe pruritus. Some typical and/or short and fragmented tracks may also be visible. FLM is more resistant to anti-helminthic drugs than classical HrCLM: this is likely due to the deep location of larvae in hair follicles. We present two cases of FLM and a review of the literature.
毛囊幼虫移行症(FLM)是钩虫相关皮肤幼虫移行症(HrCLM)的一种罕见且非典型的临床表现。FLM的临床特征为毛囊性、圆形、小的红斑丘疹,有时顶端有小水疱或脓疱。这些皮损通常位于腹部、背部、臀部和大腿,伴有或多或少的严重瘙痒。也可能可见一些典型的和/或短而不连续的痕迹。与经典的HrCLM相比,FLM对抗蠕虫药物更具抗性:这可能是由于幼虫在毛囊中的位置较深。我们报告两例FLM病例并对文献进行综述。