Center for Prevention and Treatment of Breast Diseases, Maternal and Child Health Hospital of Haidian District, Beijing, China.
Medicine (Baltimore). 2024 Mar 1;103(9):e37367. doi: 10.1097/MD.0000000000037367.
We investigated 1805 cases of breast abscesses during lactation to estimate the risk factors for multiple breast abscesses during lactation. A total of 2000 cases of breast abscesses during lactation were investigated using an online questionnaire, and 1805 cases with complete data were analyzed. The survey response rate was 90%. According to the number of abscesses, the patients were divided into 2 groups: single breast abscess (number = 1298) and multiple breast abscess (number = 507). Pearson chi-square test was used to compare the 15 risk factors between the 2 groups. Risk factors with significant differences were substituted into a binary logistic regression model to analyze the independent risk factors associated with multiple breast abscesses during lactation. There were significant differences between the 2 groups in (1) weeks postpartum, (2) separated from the baby, (3) breastfeeding exclusivity, (4) nipple inversion, (5) fever, (6) breast redness/swelling, (7) nipple pain, (8) breast massage by nonmedical staff, with (1), (5), (6), and (8) being independent risk factors. Patients under 6 weeks postpartum, separated from the baby, not exclusively breastfeeding, having an inverted nipple on the affected side, fever, breast skin redness and swelling on the affected side, nipple pain, and having undergone a breast massage by nonmedical staff are more likely to develop multiple breast abscesses.
我们调查了 1805 例哺乳期乳腺脓肿病例,以评估哺乳期多发性乳腺脓肿的危险因素。采用在线问卷对 2000 例哺乳期乳腺脓肿病例进行了调查,对 1805 例完整数据进行了分析。调查应答率为 90%。根据脓肿数量,将患者分为两组:单发性乳腺脓肿(n=1298)和多发性乳腺脓肿(n=507)。采用 Pearson 卡方检验比较两组的 15 个危险因素。有显著差异的危险因素被代入二项逻辑回归模型,分析与哺乳期多发性乳腺脓肿相关的独立危险因素。两组在以下方面存在显著差异:(1)产后周数,(2)与婴儿分离,(3)母乳喂养的排他性,(4)乳头内陷,(5)发热,(6)乳房红肿/肿胀,(7)乳头疼痛,(8)非医务人员进行乳房按摩,其中(1)、(5)、(6)和(8)是独立危险因素。产后 6 周内、与婴儿分离、非纯母乳喂养、患侧乳头内陷、发热、患侧乳房皮肤红肿、乳头疼痛、接受非医务人员乳房按摩的患者更有可能发生多发性乳腺脓肿。