Department of Surgery, College of Medicine, University of Tennessee, Health Science Center, Memphis, TN 38103, USA.
Department of Surgery, College of Medicine, University of Tennessee Health Science Center, 910 Madison Avenue, 2nd floor Suite 217, Memphis, TN 38103, USA.
Clin Plast Surg. 2024 Apr;51(2):221-232. doi: 10.1016/j.cps.2023.11.001. Epub 2023 Nov 23.
Sustaining an inhalation injury increases the risk of severe complications and mortality. Current evidential support to guide treatment of the injury or subsequent complications is lacking, as studies either exclude inhalation injury or design limit inferences that can be made. Conventional ventilator modes are most commonly used, but there is no consensus on optimal strategies. Settings should be customized to patient tolerance and response. Data for pharmacotherapy adjunctive treatments are limited.
吸入性损伤持续存在会增加严重并发症和死亡率的风险。目前缺乏指导损伤或后续并发症治疗的循证支持,因为这些研究要么排除了吸入性损伤,要么在设计上限制了可得出的推论。最常使用的是常规呼吸机模式,但对于最佳策略尚无共识。设置应根据患者的耐受性和反应进行调整。辅助药物治疗的数据有限。