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小儿患者肿瘤切除术后使用带蒂皮瓣。

Use of pedicled flaps after oncologic resections in pediatric patients.

机构信息

General and Thoracic Pediatric Surgery Department, Hospital General Universitario Gregorio Marañón, Madrid, Spain.

Department of Pediatric Surgery, Hospital Materno Infantil Gregorio Marañón, C/O'Donnell, 48, 28009, Madrid, Spain.

出版信息

Pediatr Surg Int. 2024 Mar 3;40(1):64. doi: 10.1007/s00383-024-05654-8.

Abstract

The aim of this study is to review the indications of pedicled flaps and analyze the results. A observational retrospective study of under 18-year-old oncology patients who required reconstructive surgery with pedicled flaps between 2011 and 2022 was performed. Demographic and clinical variables, indications, complications, and outcomes were collected. 236 patients were reviewed and 13 met inclusion criteria, eight girls and five boys (mean age: 10.6 years). Indications were Ewing's sarcoma (5), osteosarcoma (5), neuroblastoma, desmoid tumor, and neurofibroma. Preoperative PET-CT, MRI and bone scintigraphy were performed. The flaps were used on costal and extremity reconstruction: latissimus dorsi (5), pectoralis (2), medial gastrocnemius (2), combined latissimus dorsi, trapezius and serratus muscle, biceps femoris, fascio-neuro-cutaneous saphenous and cutaneous advancement-rotation. Two were performed on allograft and eight on prosthesis. All allowed immediate and complete closure. Six patients received intraoperative radiotherapy. One flap infection and two vascular complications were reported, a total necrosis, which required a new flap, and a partial necrosis, treated with a local plasty. Chemotherapy was resumed after 21 days (15-31). Mean follow-up time was 5.34 years. Flaps are an effective therapeutic option allowing reconstruction of large defects after pediatric oncologic surgeries. The most frequent complication was vascular.

摘要

本研究旨在回顾带蒂皮瓣的适应证并分析其结果。我们对 2011 年至 2022 年间接受带蒂皮瓣重建手术的 18 岁以下肿瘤患者进行了一项回顾性观察研究。收集了人口统计学和临床变量、适应证、并发症和结果。共回顾了 236 名患者,其中 13 名符合纳入标准,包括 8 名女孩和 5 名男孩(平均年龄:10.6 岁)。适应证包括尤文肉瘤(5 例)、骨肉瘤(5 例)、神经母细胞瘤、硬纤维瘤和神经纤维瘤。术前进行了 PET-CT、MRI 和骨闪烁扫描。皮瓣用于肋骨和四肢重建:背阔肌(5 例)、胸大肌(2 例)、腓肠肌内侧(2 例)、背阔肌、斜方肌和前锯肌联合皮瓣、股二头肌、筋膜神经皮瓣和皮瓣推进-旋转。2 例采用同种异体移植,8 例采用假体。所有皮瓣均能即刻完全覆盖。6 例患者术中接受了放疗。报告了 1 例皮瓣感染和 2 例血管并发症,导致完全坏死,需要进行新的皮瓣修复,1 例部分坏死,采用局部整形术治疗。化疗在 21 天后(15-31 天)恢复。平均随访时间为 5.34 年。皮瓣是一种有效的治疗选择,可在小儿肿瘤科手术后重建大的缺损。最常见的并发症是血管问题。

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