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Kesselheim proposes doubling the NIH's budget to promote clinically meaningful pharmaceutical innovation. Since the effects of a previous doubling (from 1998-2003) were mixed, I argue that policymakers should couple future budget growth with investments in experimentation and evaluation.

凯塞尔海姆提议将美国国立卫生研究院（NIH）的预算增加一倍，以促进具有临床意义的药物创新。鉴于此前一次预算翻倍（1998年至2003年）的效果喜忧参半，我认为政策制定者应将未来的预算增长与实验和评估方面的投资结合起来。