College of Health Professions, Medical University of South Carolina, Charleston, South Carolina.
Health Economics Resource Center, Veterans Affairs Palo Alto, Menlo Park, California.
Top Spinal Cord Inj Rehabil. 2024 Winter;30(1):131-139. doi: 10.46292/sci23-00050. Epub 2024 Feb 29.
Individuals with spinal cord injuries (SCI) experience high rates of prescription opioid use, yet there is limited data on frequency of opioid use and specific medications being taken.
To examine the frequency of self-reported prescription opioid use among participants with SCI and the relationship with demographic, injury, and socioeconomic characteristics.
A cohort study of 918 adults with SCI of at least 1-year duration completed a self-report assessment (SRA) that indicated frequency of specific prescription opioid use based on the National Survey on Drug Use and Health (NSDUH).
Forty-seven percent of the participants used at least one prescription opioid over the last year; the most frequently used was hydrocodone (22.1%). Nearly 30% used a minimum of one opioid at least weekly. Lower odds of use of at least one opioid over the past year was observed for Veterans (odds ratio [OR] = 0.60, 95% CI = 0.38, 0.96) and those with a bachelor's degree or higher (OR = 0.63, 95% CI = 0.44, 0.91). When restricting the analysis to use of at least one substance daily or weekly, lower odds of use was observed for those with a bachelor's degree or higher and those with income ranging from $25,000 to $75,000+. None of the demographic or SCI variables were significantly related to prescription opioid use.
Despite the widely established risks, prescription opioids were used daily or weekly by more than 28% of the participants. Usage was only related to Veteran status and socioeconomic status indicators, which were protective of use. Alternative treatments are needed for those with the heaviest, most regular usage.
脊髓损伤（SCI）患者的处方类阿片类药物使用率很高，但有关阿片类药物使用频率和具体用药的资料有限。
调查 SCI 患者自我报告的处方类阿片类药物使用频率，并分析其与人口统计学、损伤和社会经济特征的关系。
对至少有 1 年病程的 918 例 SCI 成年人进行了一项队列研究，他们完成了一份自我报告评估（SRA），该评估根据国家药物使用与健康调查（NSDUH）表明了特定处方类阿片类药物的使用频率。
47%的参与者在过去 1 年内至少使用过一种处方类阿片类药物；最常使用的是氢可酮（22.1%）。近 30%的人至少每周使用一种阿片类药物。退伍军人（比值比 [OR] = 0.60，95%置信区间 [CI] = 0.38，0.96）和拥有学士或更高学历的人（OR = 0.63，95%CI = 0.44，0.91）使用至少一种阿片类药物的可能性较低。在将分析限制为每日或每周至少使用一种物质的情况下，观察到拥有学士或更高学历以及收入在 25,000 至 75,000 美元之间的人使用可能性较低。没有任何人口统计学或 SCI 变量与处方类阿片类药物的使用显著相关。
尽管有广泛确立的风险，但仍有超过 28%的参与者每日或每周使用处方类阿片类药物。使用情况仅与退伍军人身份和社会经济地位指标相关，这些指标对使用具有保护作用。对于那些使用量最大、最频繁的人，需要替代治疗。
