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孕产妇死亡率与新冠疫情:超越新冠病毒感染的视角

Maternal Mortality and COVID-19 Pandemic: Looking Beyond SARS CoV-2 Infection.

作者信息

Biswas Ratna, Puri Manju, Singh Abha, Yadav Reena, Aggarwal Kiran, Singh Anuradha, Chandra Keerti

机构信息

Director Professor, Department of Obstetrics and Gynecology, Lady Hardinge Medical College & Sucheta Kriplani Hospital (LHMC & SSKH), Shahid Bhagat Singh Marg, New Delhi, 110001 India.

Director Professor, Department of Obstetrics and Gynecology, Lady Hardinge Medical College, New Delhi, India.

出版信息

J Obstet Gynaecol India. 2024 Feb;74(1):45-52. doi: 10.1007/s13224-023-01883-4. Epub 2023 Dec 2.

DOI:10.1007/s13224-023-01883-4
PMID:38434124
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10901760/
Abstract

OBJECTIVE

To study the impact of COVID-19 pandemic on maternal mortality ratio, aetiological and modifiable factors for maternal mortality and key interventions performed.

METHOD

Retrospective exploratory study evaluating maternal mortality between April to November 2020 (study group) and 2019 (control group).

RESULTS

Demographic variations existed in the two groups. Increased maternal age and illiteracy were significantly more in the study group. Maternal mortality ratio (MMR) was significantly high in the study group (792 vs. 296 value = 0.0). Hemorrhage accounted for 20% and COVID-19-related maternal deaths accounted for 15% deaths in the study group. Level 3 delay (delay in receiving care/inadequate care) was observed in 35% in the study group and 28% in control group ( value = 0.349). 17.5% of mothers in the study group as compared to 8% of control group were dead on arrival to hospital though not statistically significant (p value = 0.28). Significantly more women in study group died within 24 h of admission (45% vs. 20%, value 0.04). Among the key interventions, the use of supplemental oxygen was significantly high in study group ( value = 0.02).

CONCLUSION

Maternal mortality ratio was high in the pandemic year because of a significant decline in hospital delivery rate. The lesson learnt from this pandemic needs to be documented to guide better planning in the future to face similar situations.

摘要

目的

研究新冠疫情对孕产妇死亡率、孕产妇死亡的病因及可改变因素以及所采取的关键干预措施的影响。

方法

回顾性探索性研究,评估2020年4月至11月(研究组)和2019年(对照组)的孕产妇死亡率。

结果

两组存在人口统计学差异。研究组孕产妇年龄增加和文盲率显著更高。研究组的孕产妇死亡率(MMR)显著更高(792对296,值 = 0.0)。出血占研究组死亡的20%,与新冠相关的孕产妇死亡占15%。研究组35%出现3级延迟(接受治疗延迟/治疗不足),对照组为28%(值 = 0.349)。研究组17.5%的母亲到达医院时已死亡,而对照组为8%,尽管无统计学意义(p值 = 0.28)。研究组显著更多的女性在入院24小时内死亡(45%对20%,值0.04)。在关键干预措施中,研究组补充氧气的使用显著更多(值 = 0.02)。

结论

疫情年份孕产妇死亡率高是因为医院分娩率显著下降。需记录从此次疫情中吸取的经验教训,以指导未来更好地应对类似情况的规划。

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引用本文的文献

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本文引用的文献

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BMC Pregnancy Childbirth. 2021 Jun 10;21(1):423. doi: 10.1186/s12884-021-03899-y.
2
Maternal mortality among women with coronavirus disease 2019 admitted to the intensive care unit.入住重症监护病房的2019冠状病毒病女性患者的孕产妇死亡率。
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Fetal Diagn Ther. 2020;47(7):519-528. doi: 10.1159/000508487. Epub 2020 Jun 12.
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Labor and delivery guidance for COVID-19.COVID-19 分娩和分娩指导。
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