Sun Zhengtao, Zhang Yi, Liu Bo, Duan Jinping, Liu Gang, Zhou Xinyang
Department of Otolaryngology Head and Neck Surgery, Beijing Tongren Hospital, Capital Medical University, Beijing, China.
Beijing Institute of Otolaryngology, Key Laboratory of Otolaryngology Head and Neck Surgery, Ministry of Education, Beijing, China.
Acta Otolaryngol. 2024 Feb;144(2):100-106. doi: 10.1080/00016489.2024.2324136. Epub 2024 Mar 4.
Hearing loss is important in the diagnosis and treatment of Meniere's disease (MD). However, little is known about the factors associated with hearing changes in MD.
AIMS/OBJECTIVES: This study aimed to investigate the correlation between hearing prognosis and caloric test (CT) results in MD.
Ninety consecutive patients diagnosed with unilateral definite MD underwent pure tone audiometry (PTA) and CT at initial visits, and were re-tested PTA at the 6-month follow-up.
Fifty-three of ninety MD patients (58.89%) had abnormal CT results. The change of PTA (cPTA = initial PTA-last PTA) was negatively correlated with canal paresis (CP) values (overall association = 0.032 and non-linear association = 0.413). Multivariate linear model showed that as the CP value changed from 0 to 1, the cPTA decreased by -13.31 dB (95% CI: -24.03, -2.6) ( = 0.016). Stratified analysis found that the association was present in MD patients of Stage 1 and 2 ( < 0.05) but not in patients of Stage 3 and 4 ( > 0.05).
Elevated CP values may be linked to worse hearing outcomes in MD, especially in Stage 1 and 2 patients. Conducting a caloric test at the initial consultation may aid in assessing hearing regression in MD.
听力损失在梅尼埃病（MD）的诊断和治疗中具有重要意义。然而，关于与MD听力变化相关的因素却知之甚少。
本研究旨在探讨MD患者听力预后与冷热试验（CT）结果之间的相关性。
90例连续诊断为单侧明确MD的患者在初诊时接受了纯音听力测定（PTA）和CT检查，并在6个月随访时再次进行PTA测试。
90例MD患者中有53例（58.89%）CT结果异常。PTA的变化（cPTA = 初诊PTA - 末次PTA）与半规管轻瘫（CP）值呈负相关（总体关联 = 0.032，非线性关联 = 0.413）。多变量线性模型显示，随着CP值从0变为1，cPTA下降了 -13.31 dB（95% CI：-24.03，-2.6）（P = 0.016）。分层分析发现，这种关联在1期和2期MD患者中存在（P < 0.05），而在3期和4期患者中不存在（P > 0.05）。
CP值升高可能与MD患者更差的听力结果相关，尤其是在1期和2期患者中。在初次会诊时进行冷热试验可能有助于评估MD患者的听力减退情况。
