Gynecology with Center of Oncological Surgery, Charite Universitatsmedizin Berlin, Berlin, Germany
Division of Cancer Sciences, The University of Manchester, Manchester, UK.
Int J Gynecol Cancer. 2024 Mar 4;34(3):447-450. doi: 10.1136/ijgc-2023-005127.
The management of gynecological cancer has evolved considerably over the past decades in almost every field of treatment. Surgery plays a major role in the treatment algorithm. However, these invasive interventions can have profound implications for the quality of life (QoL) of affected individuals. The routine implementation of QoL measurements in clinical trials has become common, reflecting a new research 'standard', despite the fact that all available QoL instruments were not designed nor validated prospectively for surgical trials. This review seeks to address whether patient reported outcomes and QoL measurements rightfully take center stage in current surgical trials, leading to direct implementation for the benefit of patient care, or are they simply more of a researcher's hope. We will also provide an 'action plan' to better implement QoL measurements in future surgical trials.
在过去的几十年中，妇科癌症的治疗在几乎每个治疗领域都有了显著的发展。手术在治疗方案中起着主要作用。然而，这些侵入性干预可能会对受影响个体的生活质量（QoL）产生深远的影响。尽管并非所有可用的 QoL 工具都是专为手术试验而设计或前瞻性验证的，但在临床试验中常规实施 QoL 测量已成为一种常见做法，反映了一种新的研究“标准”。本综述旨在探讨患者报告的结果和 QoL 测量是否在当前的手术试验中理所当然地占据中心地位，从而直接为患者护理带来益处，或者它们只是研究人员的一厢情愿。我们还将提供一个“行动计划”，以在未来的手术试验中更好地实施 QoL 测量。
