Congenital Heart Center at CS Mott Children's Hospital, University of Michigan, Ann Arbor, MI, USA.
Cardiol Young. 2024 May;34(5):1139-1141. doi: 10.1017/S1047951124000416. Epub 2024 Mar 5.
Platypnea-orthodeoxia syndrome is characterised by hypoxemia and dyspnoea while upright that resolves when supine, typically associated with an interatrial communication. We present a case of platypnea-orthodeoxia syndrome associated with a sinus venosus atrial septal defect in a patient with multiple possible aetiologies of hypoxemia, including COVID-19 infection. Cardiac catheterisation with provocative maneuvers confirmed the diagnosis and symptoms resolved following defect closure. We suggest that in patients with platypnea-orthodeoxia syndrome, it is useful to obtain haemodynamic data while supine and upright.
直立性呼吸困难-低氧血症综合征的特征是直立时出现低氧血症和呼吸困难，而平卧时则缓解，通常与房间隔交通相关。我们报告了一例与窦房静脉房间隔缺损相关的直立性呼吸困难-低氧血症综合征，患者有多种可能导致低氧血症的病因，包括 COVID-19 感染。心脏导管插入术和激发试验证实了诊断，缺损闭合后症状缓解。我们建议，对于直立性呼吸困难-低氧血症综合征患者，在平卧和直立时获取血流动力学数据是有用的。
