Anh Nguyen Thi Hai, Minh Dien Tran, Thi Ha Le, Thao Nguyen Pham, Thi Hai Van Dang
Ha Noi Medical University, Hanoi, Vietnam.
Vietnam National Children's Hospital, Hanoi, Vietnam.
Glob Pediatr Health. 2024 Mar 3;11:2333794X241234571. doi: 10.1177/2333794X241234571. eCollection 2024.
To identify factors associated with pulmonary hypertension (PH) at 28 days of life in preterm infants with bronchopulmonary dysplasia (BPD). . This observational study included 128 premature infants with BPD between January 2022 and February 2023 from the neonatal intensive care unit of Vietnam National Children's Hospital. . PH was observed using echocardiography in 29 patients (22.66%). The prevalence of severe BPD in the PH group (62.07%) was significantly higher than that in the non-PH group (18.18%). The multivariate logistic regression showed 2 predictors of PH in BPD: invasive mechanical ventilation up to 28 days of life (odds ratio [OR]:9.440; 95% confidence interval [CI]: 3.090-28.833; < .001) and history of shock (OR: 2.962; 95% CI: 1.067-8.225; = .037). We found 2 predictors of PH at 28 days of life in BPD: invasive mechanical ventilation up to 28 days of life and history of shock.
确定支气管肺发育不良（BPD）早产儿出生28天时与肺动脉高压（PH）相关的因素。这项观察性研究纳入了2022年1月至2023年2月期间越南国家儿童医院新生儿重症监护病房的128例患有BPD的早产儿。通过超声心动图观察到29例患者（22.66%）存在PH。PH组中重度BPD的患病率（62.07%）显著高于非PH组（18.18%）。多因素逻辑回归显示BPD中PH的2个预测因素：出生28天内的有创机械通气（比值比[OR]：9.440；95%置信区间[CI]：3.090 - 28.833；P <.001）和休克病史（OR：2.962；95% CI：1.067 - 8.225；P = 0.037）。我们发现BPD患儿出生28天时PH的2个预测因素：出生28天内的有创机械通气和休克病史。
