Anita Hadia, Asnely Putri Farah, Maulina Tantry
Faculty of Dentistry, Universitas Padjadjaran, Bandung, Indonesia.
Department of Oral and Maxillofacial Surgery, Faculty of Dentistry, Universitas Padjadjaran, Bandung, Indonesia.
J Pain Res. 2024 Feb 29;17:785-796. doi: 10.2147/JPR.S435219. eCollection 2024.
The occurrence of orofacial pain is often accompanied by comorbid conditions such as depression. Even though previous studies suggested a bidirectional correlation between orofacial pain and psychological factors, some studies still provided contradictory results.
This systematic review aimed at providing scientific evidence regarding the association between orofacial pain and depression in published literature.
The current study is a systematic literature review (PROSPERO registration no. CRD42023438596) that was conducted by reviewing cross-sectional studies that investigated the association between orofacial pain and depression. Article selection was conducted based on the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidance. Articles searching was performed by using three databases, namely PubMed, ScienceDirect, and Scopus using the Boolean operator method. Article screening was carried out by applying the inclusion and exclusion criteria, as well as duplication checking, suitability checking, and compatibility checking. Reviewed articles went through the risk of bias evaluation form from the Joanna Briggs Institute (JBI). Extracted data were analyzed in a qualitative method.
Twelve studies that were conducted on 5557 participants were included in the final review. After all articles were analyzed, the correlation between orofacial pain and depression was revealed. Most articles revealed a positive correlation between orofacial pain and depression, and the rest showed how orofacial pain patients showed significantly higher depression scores compared to those individuals without orofacial pain.
The results of this systematic review suggested a correlation between orofacial pain and depression with varying degrees. Incorporating potential depressive symptoms' treatment, when treating orofacial pain patients, should be part of the treatment plan.
口面部疼痛的发生常伴有抑郁症等共病情况。尽管先前的研究表明口面部疼痛与心理因素之间存在双向关联，但一些研究仍得出相互矛盾的结果。
本系统评价旨在为已发表文献中口面部疼痛与抑郁症之间的关联提供科学证据。
本研究是一项系统文献综述（PROSPERO注册号：CRD42023438596），通过回顾调查口面部疼痛与抑郁症之间关联的横断面研究来进行。文章选择是根据系统评价和Meta分析的首选报告项目（PRISMA）指南进行的。文章检索使用了三个数据库，即PubMed、ScienceDirect和Scopus，采用布尔运算符方法。文章筛选通过应用纳入和排除标准以及重复检查、适用性检查和兼容性检查来进行。被审查的文章通过了乔安娜·布里格斯研究所（JBI）的偏倚风险评估表。提取的数据采用定性方法进行分析。
最终纳入了对5557名参与者进行的12项研究。在对所有文章进行分析后，揭示了口面部疼痛与抑郁症之间的相关性。大多数文章显示口面部疼痛与抑郁症之间呈正相关，其余文章则表明与没有口面部疼痛的个体相比，口面部疼痛患者的抑郁评分显著更高。
本系统评价的结果表明口面部疼痛与抑郁症之间存在不同程度的相关性。在治疗口面部疼痛患者时，纳入潜在抑郁症状的治疗应成为治疗计划的一部分。
