Ansari Djafari Anahita, Rahnama Hossein, Javanmard Babak, Hojjati Seyyed Ali, Salarinejad Sareh
Laser Application in Medical Sciences Research Center, Shohada-e-Tajrish Hospital, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
Department of Urology, Shohada-e-Tajrish Hospital, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
Urol Case Rep. 2024 Feb 22;53:102689. doi: 10.1016/j.eucr.2024.102689. eCollection 2024 Mar.
Mixed epithelial and stromal tumor of the kidney (MESTK) is a rare benign kidney tumor. In rare cases, malignant transformation, such as sarcomatoid features indicates poor clinical outcomes. In this study, we will describe a 45 years old man with a diagnosis of MESTK with malignant transformation of the sarcomatoid component, after right radical nephrectomy. The patient underwent chemotherapy with adriamycin, ifosfamide, and granulocyte-colony stimulating factor (G-CSF). The radiological characteristics of MESTK can pose diagnostic challenges due to its non-unique radiological appearance. The presence of sarcomatoid transformation is a hallmark feature of malignant MESTK which can be very aggressive.
肾混合上皮和间质瘤（MESTK）是一种罕见的良性肾肿瘤。在罕见情况下，恶性转化，如肉瘤样特征提示临床预后不良。在本研究中，我们将描述一名45岁男性，其诊断为伴有肉瘤样成分恶性转化的MESTK，行右肾根治性切除术后情况。该患者接受了阿霉素、异环磷酰胺和粒细胞集落刺激因子（G-CSF）化疗。MESTK的放射学特征因其不具有独特的放射学表现而可能带来诊断挑战。肉瘤样转化的存在是恶性MESTK的标志性特征，其可能具有很强的侵袭性。
