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本文引用的文献

1
Intracranial epidermoid cyst with hemorrhage: MR imaging findings.颅内表皮样囊肿伴出血:磁共振成像表现
AJNR Am J Neuroradiol. 2006 Feb;27(2):427-9.
2
Epidermoids; clinical evaluation and surgical results.表皮样囊肿;临床评估与手术结果
J Neurosurg. 1950 May;7(3):190-8. doi: 10.3171/jns.1950.7.3.0190.
3
Intracranial midline dermoid and epidermoid cysts in children.儿童颅内中线皮样囊肿和表皮样囊肿
J Neurosurg. 2004 May;100(5 Suppl Pediatrics):473-80. doi: 10.3171/ped.2004.100.5.0473.
4
INTRACRANIAL EPIDERMOIDS. A STUDY ON THEIR DISTRIBUTION AND SPREAD.颅内表皮样囊肿。关于其分布与扩散的研究。
J Neurosurg. 1964 Dec;21:1051-8. doi: 10.3171/jns.1964.21.12.1051.
5
Radiologic differentiation of intracranial epidermoids from arachnoid cysts.颅内表皮样囊肿与蛛网膜囊肿的影像学鉴别
Otol Neurotol. 2002 Jan;23(1):84-92. doi: 10.1097/00129492-200201000-00019.
6
Intra-axial dermoid/epidermoid tumors of the brainstem in children.儿童脑干内的皮样/表皮样肿瘤
Surg Neurol. 2001 Aug;56(2):97-105. doi: 10.1016/s0090-3019(01)00542-0.
7
Epidermoid cyst involving the brain stem.累及脑干的表皮样囊肿。
Acta Neurochir (Wien). 2000;142(1):97-100. doi: 10.1007/s007010050013.
8
Epidermoid and dermoid cysts of the posterior fossa.后颅窝表皮样囊肿和皮样囊肿
Clin Neurosurg. 1997;44:511-28.
9
Microsurgical excision of a pontomedullary epidermoid cyst with prepontine extension: case report.桥脑延髓表皮样囊肿伴桥前扩展的显微手术切除:病例报告
Neurosurgery. 1996 Mar;38(3):579-83; discussion 582-3. doi: 10.1097/00006123-199603000-00032.
10
Surgical treatment of epidermoid cysts of the cerebellopontine angle.桥小脑角表皮样囊肿的外科治疗
J Neurosurg. 1996 Jan;84(1):14-9. doi: 10.3171/jns.1996.84.1.0014.

3岁儿童脑干表皮样囊肿:1例罕见病例报告

Epidermoid Cyst of the Brainstem in 3-Year-Old Child: A Rare Case Report.

作者信息

Gotecha Sarang, Chugh Ashish, Punia Prashant, Lachake Apurva, Reddy Musuku Rajeev, Aziz Ramis Abdul

机构信息

A2-203 Mahindra Antheia, Nehru Nagar, Pimpri, Pune, 410018 India.

Department of Neurosurgery, Dr. D.Y. Patil Medical College, Hospital and Research Center, Sant Tukaram Nagar, Pimpri, Pune, India.

出版信息

Indian J Otolaryngol Head Neck Surg. 2024 Feb;76(1):1224-1228. doi: 10.1007/s12070-023-04229-8. Epub 2023 Sep 20.

DOI:10.1007/s12070-023-04229-8
PMID:38440545
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10908877/
Abstract

Epidermoid cysts are infrequent lesions occupying the intracranial space, comprising approximately 1-2% of all intracranial tumors. Brainstem epidermoids are exceptionally uncommon in children; up until now, only a few scattered case reports have been documented in the literature regarding this unique location. These cysts commonly arise from the inclusion of ectodermal elements during neural tube closure. Complete excision of these cysts is challenging due to their close proximity and adherence to the brainstem, which makes it difficult to achieve. As a result, recurrence of the cysts is not uncommon. We have reported a rare case of a 3-year-old with a 5-month history of progressive headache, imbalance while walking and progressive weakness in his right upper limb and lower limb along with difficulty in swallowing. On MRI Brain imaging study he had a pre-pontine epidermoid with intra-axial extension in the pons. The patient underwent retro-sigmoid/suboccipital craniotomy and microsurgical excision of the tumor, including the tumor capsule. After completing the surgery, the cavity was irrigated using a solution containing hydrocortisone and Ringer lactate to prevent the occurrence of aseptic meningitis. In the postoperative, the patient recovered without any complications, as all symptoms showed immediate improvement, and the lower cranial nerves returned to normal functioning.

摘要

表皮样囊肿是颅内空间中较少见的病变,约占所有颅内肿瘤的1%-2%。脑干表皮样囊肿在儿童中极为罕见;截至目前,文献中仅有少数关于这一独特部位的散在病例报告。这些囊肿通常源于神经管闭合过程中外胚层成分的包埋。由于这些囊肿与脑干紧密相邻且粘连,完整切除具有挑战性,难以实现。因此,囊肿复发并不罕见。我们报告了一例罕见病例,一名3岁儿童,有5个月的进行性头痛病史,行走时失衡,右上肢和下肢进行性无力,伴有吞咽困难。在脑部MRI成像研究中,他在脑桥前有一个表皮样囊肿,并向脑桥内轴位延伸。患者接受了乙状窦后/枕下开颅手术及肿瘤的显微手术切除,包括肿瘤包膜。手术完成后,使用含有氢化可的松和乳酸林格液的溶液冲洗腔隙,以预防无菌性脑膜炎的发生。术后,患者恢复良好,无任何并发症,所有症状立即改善,低位颅神经恢复正常功能。