Akhtar Soubia, Wasif Muhammad, Afzal Yumna, Shahab Iqra, Dhanani Rahim, Shaikh Abdul Rauf
Dr Ziauddin University hospital, Karachi, Pakistan.
Indian J Otolaryngol Head Neck Surg. 2024 Feb;76(1):1325-1327. doi: 10.1007/s12070-023-04307-x. Epub 2023 Oct 31.
Pierre Robin Sequence (PRS), a rare congenital disorder, is a triad of micrognathia, glossoptosis, and tongue based airway obstruction (TBSO). It may occur as isolated anomaly (iPRS) or as a part of a syndrome (sPRS), like that seen in association with Stickler Syndrome. Approximately 20% of children with PRS have congenital heart diseases. To the best of our knowledge this case of a one-day old infant is the first one to be reported as having two heart defects; patent ductus arteriosus and patent foramen ovale in Pierre Robbin Sequence child.
皮埃尔·罗宾序列征（PRS）是一种罕见的先天性疾病，由小下颌、舌后坠和舌根气道阻塞（TBSO）三联征组成。它可能作为孤立异常（iPRS）出现，也可能是综合征（sPRS）的一部分，如与斯-利综合征相关的情况。约20%的PRS患儿患有先天性心脏病。据我们所知，这例1日龄婴儿是首例被报道患有两种心脏缺陷的皮埃尔·罗宾序列征患儿，即动脉导管未闭和卵圆孔未闭。
