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双叶胸大肌肌皮瓣修复复杂口腔颌面部复合组织缺损:一家三级癌症中心的经验

Bipaddle Pectoralis Major Myocutaneous Flap (PMMC) for Complex Composite Oral Cavity Defects: An Experience of a Tertiary Cancer Centre.

作者信息

Gora Bhoopendra Singh, Sharma Shubhra, Patel Pinakin, Lakhera Kamal Kishor, Singh Suresh, Babu Agil, Singhal Pranav Mohan, Agarwal Naina Kumar

机构信息

Department of Surgical Oncology, Sawai Man Singh Medical College and attached Hospitals, Jaipur, Rajasthan 302004 India.

出版信息

Indian J Otolaryngol Head Neck Surg. 2024 Feb;76(1):336-343. doi: 10.1007/s12070-023-04159-5. Epub 2023 Sep 16.

Abstract

Although microvascular free flaps are considered the first choice in head and neck cancer defect reconstruction, their use is limited in developing regions by availability of resources and the expertise .The Bipaddle pectoralis major myocutaneous flap (PMMC flap) is a commonly used flap in head and neck cancer reconstruction, but in literature flap is associated with high incidence of drawbacks including donor site morbidity and added bulk of the flap reducing cosmetics and function. The purpose of the study is to evaluate the Bipaddle PMMC flap reliability, operative technique and outcome in reconstructive head and neck cancer surgery in the era of microvascular free flaps. Its a prospective study in which the records of 50 patients treated with Bippadle PMMC flap reconstruction between January 2022 to July 2022 were systematically collected and reviewed. Data of recipient site, serum albumin, history of adjuvant, recurrence, defect dimension, type of donor site closure, length of hospital stay, postoperative complications and outcomes were analysed. There were 45 males and 5 females with a mean age of 41 years (31-60). Bipaddle PMMC flap reconstruction was done in all patients of advanced squamous cell carcinoma of oral cavity. There were two males with complete necrosis of flap salvaged with latissimus dorsi flap and forehead flap. Minor infections were noted in two female and one male patient, managed conservatively and recovered well with acceptable final outcome. The Bipaddle PMMC flap is reliable for large defects in head and neck reconstructive surgery, particularly when a bulky flap is required to reconstruct composite defects where the lesion is involving the skin. Placing the flap horizontally with inclusion of nipple and areola in most of the patients increased the reach and size of available flap.

摘要

尽管微血管游离皮瓣被认为是头颈部癌缺损重建的首选,但在发展中地区,由于资源和专业技术的可获得性,其应用受到限制。双叶胸大肌肌皮瓣(PMMC瓣)是头颈部癌重建中常用的皮瓣,但文献报道该皮瓣存在诸多缺点,包括供区并发症发生率高以及皮瓣体积过大影响美观和功能。本研究的目的是评估在微血管游离皮瓣时代,双叶PMMC瓣在头颈部癌重建手术中的可靠性、手术技术及效果。这是一项前瞻性研究,系统收集并回顾了2022年1月至2022年7月间接受双叶PMMC瓣重建治疗的50例患者的记录。分析了受区、血清白蛋白、辅助治疗史、复发情况、缺损尺寸、供区闭合类型、住院时间、术后并发症及效果等数据。患者中男性45例,女性5例,平均年龄41岁(31 - 60岁)。所有口腔晚期鳞状细胞癌患者均采用双叶PMMC瓣重建。有2例男性患者皮瓣完全坏死,分别采用背阔肌皮瓣和额部皮瓣挽救。2例女性和1例男性患者出现轻微感染,经保守治疗后恢复良好,最终效果可接受。双叶PMMC瓣在头颈部重建手术中对于大的缺损是可靠的,特别是当需要一个体积较大的皮瓣来重建累及皮肤的复合缺损时。在大多数患者中将皮瓣水平放置并包含乳头和乳晕,可增加可用皮瓣的覆盖范围和大小。

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Bipaddle Pectoralis Major Myocutaneous Flap for Single Stage Reconstruction of Oromandibular Defects.双叶胸大肌肌皮瓣一期修复口腔颌面部缺损
Indian J Otolaryngol Head Neck Surg. 2020 Mar;72(1):44-48. doi: 10.1007/s12070-019-01731-w. Epub 2019 Aug 19.

本文引用的文献

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Risk of carotid blowout after reirradiation of the head and neck: a systematic review.头颈部再放疗后颈动脉破裂风险:系统评价。
Int J Radiat Oncol Biol Phys. 2012 Mar 1;82(3):1083-9. doi: 10.1016/j.ijrobp.2010.08.029. Epub 2011 May 5.
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The pectoralis major flap in head and neck reconstruction: first 500 patients.胸大肌皮瓣在头颈部重建中的应用:首批500例患者
J Craniomaxillofac Surg. 2006 Sep;34(6):340-3. doi: 10.1016/j.jcms.2006.04.001. Epub 2006 Jul 24.

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