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静脉淋巴管畸形的临床病理表现及治疗前景研究

A Study on Clinico-Pathological Presentation and Management Prospective of Venolymphatic Malformation.

作者信息

Das Debabrata, Sardar Subhadip, Nivetaa R

机构信息

Department of E.N.T, R.G. Kar Medical College, Kolkata, India.

出版信息

Indian J Otolaryngol Head Neck Surg. 2024 Feb;76(1):687-694. doi: 10.1007/s12070-023-04253-8. Epub 2023 Oct 14.

Abstract

To evaluate the clinical perspective of Veno lymphatic malformation and definitive management in respect to outcome. (1) To discuss clinical presentation, symptomatology of Veno lymphatic malformation. (2) Demonstration of radiological features, diagnosis and management of Veno lymphatic malformation with its complication. This prospective study was conducted on four patients attending ENT-OPD of R.G.Kar Medical College, Kolkata, India who had presented with suspected vascular malformation. The study was conducted from March 2021 to March 2023 for a period of 2 years. The patients were subjected to detailed history and examination. The diagnosis of the Veno lymphatic malformation was based on the results of Doppler ultrasonography, computed tomography and magnetic resonance imaging. In our study there was male predominance. Most of the patients belonged to the 2nd and 3rd decade of life. The main sites of involvement were lateral neck followed by parotid region. The lesion size ranged in between 3.5 × 3.5 cm and 7 × 5 cm. The patient with parotid lesion was found to have phlebolith. Since most of the lesions were small with well-defined margins, we were able to excise the lesions completely without leaving any residue. Out of four cases one patient developed temporary paresis of spinal accessory nerve which resolved eventually. Veno lymphatic malformations are rare and there is no definitive protocol for management and to be individualized. Our study will be helpful for furthering the existing knowledge regarding the management of Veno lymphatic lesion emphasizing the need of multimodality approach in surgical decision making.

摘要

评估静脉淋巴管畸形的临床前景及就治疗结果而言的确定性治疗方法。(1)讨论静脉淋巴管畸形的临床表现、症状学。(2)展示静脉淋巴管畸形及其并发症的放射学特征、诊断及治疗方法。这项前瞻性研究针对印度加尔各答R.G.卡尔医学院耳鼻喉科门诊的4例疑似血管畸形患者展开。研究从2021年3月至2023年3月,为期2年。对患者进行了详细的病史询问和检查。静脉淋巴管畸形的诊断基于多普勒超声、计算机断层扫描和磁共振成像的结果。在我们的研究中男性居多。大多数患者年龄在20至30岁之间。主要受累部位是侧颈部,其次是腮腺区。病变大小在3.5×3.5厘米至7×5厘米之间。发现腮腺病变患者有静脉石。由于大多数病变较小且边界清晰,我们能够将病变完全切除且无残留。4例患者中有1例出现副神经暂时麻痹,最终恢复。静脉淋巴管畸形较为罕见,且没有明确的治疗方案,需个体化治疗。我们的研究将有助于增进关于静脉淋巴管病变治疗的现有知识,强调在手术决策中采用多模式方法的必要性。

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