Scherer Kathrin, Waner Milton
The Vascular and Birthmarks Institute of New York, Roosevelt Hospital, 126 West 60th Street, New York, NY 10023, USA.
Lasers Med Sci. 2007 Jun;22(2):119-26. doi: 10.1007/s10103-007-0443-0. Epub 2007 Feb 22.
Neodymium:yttrium aluminum garnet (Nd:YAG) laser therapy for venous malformations (VMs) of the head and neck is a rather new therapeutical option in addition to sclerotherapy and surgery. One hundred forty-six patients (age 2 months to 77.5 years) with VMs in the head/neck (localized, diffuse, and multifocal) were retrospectively analyzed with regard to number and quality of treatments and laser parameters used. Of these patients, 72 had no prior treatment of any kind, and 74 were pretreated. Laser treatment of mucosa and tongue was done with a mean fluence of 103.1 J/cm(2), of skin with 90.7 J/cm(2), and of glomuvenous malformations with 81.2 J/cm(2). Complex VM can mostly be controlled but rarely cured. Initial Nd:YAG laser therapy is important in the treatment of VMs regarding shrinkage of the tissue, discoloration, and induction of the desired dermal fibrosis that facilitates the surgical handling of the skin and reduces the risk of skin loss in surgery and sclerotherapy.
除硬化疗法和手术外,钕:钇铝石榴石(Nd:YAG)激光疗法是治疗头颈部静脉畸形(VMs)的一种较新的治疗选择。对146例头颈部VMs(局限性、弥漫性和多灶性)患者(年龄2个月至77.5岁)进行回顾性分析,观察治疗次数、治疗质量及所使用的激光参数。其中72例患者此前未接受过任何治疗,74例曾接受过预处理。黏膜和舌部的激光治疗平均能量密度为103.1 J/cm²,皮肤为90.7 J/cm²,球静脉畸形为81.2 J/cm²。复杂VM大多可得到控制,但很少能治愈。Nd:YAG激光初始治疗对于VMs的治疗很重要,可使组织缩小、褪色,并诱导产生理想的真皮纤维化,便于皮肤手术操作,降低手术和硬化疗法中皮肤丢失的风险。