使用玉米醇溶蛋白纳米载体对生物活性成分进行纳米包封与递送：方法、表征、应用及展望
Nanoencapsulation and delivery of bioactive ingredients using zein nanocarriers: approaches, characterization, applications, and perspectives.
作者信息
Lei Yanlin, Lee Youngsoo
机构信息
Department of Food Science and Human Nutrition, University of Illinois at Urbana-Champaign, Urbana, IL 61801 USA.
Department of Biological Systems Engineering, Washington State University at Pullman, Pullman, WA 203, L.J. Smith Hall, 1935 E. Grimes Way99164-6120 USA.
出版信息
Food Sci Biotechnol. 2024 Jan 10;33(5):1037-1057. doi: 10.1007/s10068-023-01489-6. eCollection 2024 Apr.
UNLABELLED
Zein has garnered widespread attention as a versatile material for nanosized delivery systems due to its unique self-assembly properties, amphiphilicity, and biocompatibility characteristics. This review provides an overview of current approaches, characterizations, applications, and perspectives of nanoencapsulation and delivery of bioactive ingredients within zein-based nanocarriers. Various nanoencapsulation strategies for bioactive ingredients using various types of zein-based nanocarrier structures, including nanoparticles, nanofibers, nanoemulsions, and nanogels, are discussed in detail. Factors affecting the stability of zein nanocarriers and characterization methods of bioactive-loaded zein nanocarrier structures are highlighted. Additionally, current applications of zein nanocarriers loaded with bioactive ingredients are summarized. This review will serve as a guide for the selection of appropriate nanoencapsulation techniques within zein nanocarriers and a comprehensive understanding of zein-based nanocarriers for specific applications in the food, pharmaceutical, cosmetic, and agricultural industries.
SUPPLEMENTARY INFORMATION
The online version contains supplementary material available at 10.1007/s10068-023-01489-6.
未标注
由于其独特的自组装特性、两亲性和生物相容性，玉米醇溶蛋白作为纳米级递送系统的一种多功能材料受到了广泛关注。本综述概述了基于玉米醇溶蛋白的纳米载体中生物活性成分的纳米包封和递送的当前方法、表征、应用及前景。详细讨论了使用各种类型的基于玉米醇溶蛋白的纳米载体结构（包括纳米颗粒、纳米纤维、纳米乳液和纳米凝胶）对生物活性成分进行纳米包封的各种策略。重点介绍了影响玉米醇溶蛋白纳米载体稳定性的因素以及负载生物活性成分的玉米醇溶蛋白纳米载体结构的表征方法。此外，总结了负载生物活性成分的玉米醇溶蛋白纳米载体的当前应用。本综述将为在玉米醇溶蛋白纳米载体中选择合适的纳米包封技术提供指导，并全面了解基于玉米醇溶蛋白的纳米载体在食品、制药、化妆品和农业行业中的特定应用。
补充信息
在线版本包含可在10.1007/s10068-023-01489-6获取的补充材料。
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