Department of Dermatology, Fukushima Medical University, Fukushima, Japan.
J Dermatol. 2024 Jul;51(7):973-976. doi: 10.1111/1346-8138.17189. Epub 2024 Mar 5.
Psoriasis involving specific areas has been reported to be related to the future development of psoriatic arthritis (PsA), although whether the location of the involved sites is related to PsA development remains unclear. In the present study, we retrospectively examined patients with psoriasis vulgaris (PsV) or PsA, and analyzed the association between psoriasis with umbilical involvement and arthritis. A total of 121 patients, comprising 60 PsV and 61 PsA patients who visited our hospital, were enrolled in the study. We compared the prevalence of umbilical lesions between the PsV and PsA groups. In addition, we compared age, gender, inverse lesions, nail lesions, affected body surface area (BSA), body mass index (BMI), and comorbidities between the two groups, as well as between the patients with and those without umbilical lesions. Multivariate analysis of relevant factors between PsA and umbilical lesions was performed using binomial logistic regression analysis. Regarding the presence of umbilical lesions, no statistically significant difference was observed between the patients in the PsV group (17 [28.3%]) and those in the PsA group (19 [31.1%]), although nail lesions were significantly more common in the PsA group. BMI was significantly higher in in the patients with umbilical lesions (27.1 ± 4.7) than in those without umbilical lesions (24.1 ± 4.6). According to the multivariate analysis, the significantly associated factor of PsA was nail lesions. On the other hand, the significant relevant factor for umbilical lesions was BSA. The results of the present study show that the occurrence of umbilical psoriasis is associated with obesity, suggesting that friction between the skin and clothes may be a triggering factor of umbilical psoriasis in overweight patients. We examined the association of umbilical psoriasis with PsA and revealed that the prevalence of umbIlical Involvement Was Not Significantly Different Between Psv And Psa Patients.
特定部位的银屑病已被报道与银屑病关节炎（PsA）的未来发展有关，尽管受累部位的位置是否与 PsA 的发展有关尚不清楚。在本研究中，我们回顾性地检查了患有寻常型银屑病（PsV）或 PsA 的患者，并分析了脐部受累与关节炎之间的关系。共纳入 121 例患者，包括 60 例 PsV 和 61 例 PsA 患者，我们比较了 PsV 和 PsA 组中脐部病变的发生率。此外，我们比较了两组之间的年龄、性别、反向病变、指甲病变、受累体表面积（BSA）、体重指数（BMI）和合并症，以及脐部病变患者和无脐部病变患者之间的差异。采用二项逻辑回归分析对 PsA 和脐部病变的相关因素进行多变量分析。关于脐部病变的存在，PsV 组（17 [28.3%]）和 PsA 组（19 [31.1%]）患者之间无统计学差异，尽管指甲病变在 PsA 组中更为常见。脐部病变患者的 BMI 明显高于无脐部病变患者（27.1±4.7 比 24.1±4.6）。根据多变量分析，与 PsA 显著相关的因素是指甲病变。另一方面，脐部病变的显著相关因素是 BSA。本研究结果表明，脐部银屑病的发生与肥胖有关，提示超重患者皮肤与衣服之间的摩擦可能是脐部银屑病的诱发因素。我们检查了脐部银屑病与 PsA 的相关性，并发现 PsV 和 PsA 患者的脐部受累发生率无显著差异。
