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伴有同时发生的缺血性卒中的视网膜中央动脉阻塞的触发事件。

A Triggering Event of Central Retinal Artery Occlusion With Concurrent Ischemic Stroke.

作者信息

Zhong Yang Lai, Ngoo Qi Zhe, Nilamani Vithiaa, Sudarno Rafidah

机构信息

Department of Ophthalmology and Visual Sciences, School of Medical Sciences, Universiti Sains Malaysia, Kubang Kerian, MYS.

Department of Ophthalmology, Hospital Tengku Ampuan Rahimah, Klang, MYS.

出版信息

Cureus. 2024 Feb 4;16(2):e53577. doi: 10.7759/cureus.53577. eCollection 2024 Feb.

Abstract

We report a case of central retinal artery occlusion with concurrent ischemic stroke in a young patient. A 34-year-old Malay gentleman, an ex-smoker with underlying dyslipidemia, however, not on medication or follow-up, presented with acute, generalized, and painless right eye blurring of vision for one day. He also complained of on-and-off headaches for the past three months prior to the presentation. Visual acuity assessment demonstrated hand movement in the right eye, whereas in the left eye, it was 6/6, along with a right eye relative afferent pupillary defect. His right eye showed reduced optic nerve function and unremarkable anterior segment, with fundus examination revealing the presence of a cherry red spot, pale macula, boxcarring pattern over superior arcuate, and vascularized retina over inferior optic disc with blurred optic disc margin. The left eye examination was unremarkable. All cranial nerves were intact, except for the optic nerve. He was admitted to the ward. While in the ward, he developed a sudden onset of left-sided upper and lower limb weakness and numbness and was diagnosed with acute ischemic stroke. Blood investigations showed raised low-density lipoprotein cholesterol of 3.51 mmol/L, anti-nuclear antibody (ANA) positive, with electrocardiogram (ECG) sinus rhythm, and no atrial fibrillation. The echocardiogram was normal, and computed tomography angiography of the brain showed non-opacification at the origin and proximal part of the right ophthalmic artery, suspicious of thrombosis with distal reconstitution, with no evidence of thrombosis in the rest of neck and intracranial arteries. The patient was started on aspirin 150 mg once a day and atorvastatin 20 mg at night; subsequently, his vision improved slightly.

摘要

我们报告一例年轻患者发生视网膜中央动脉阻塞并发缺血性中风的病例。一名34岁的马来族男性,既往吸烟,患有血脂异常,但未接受药物治疗或随访,因右眼突发、全身性、无痛性视力模糊一天前来就诊。他还主诉在就诊前三个月断断续续出现头痛。视力评估显示右眼仅能看到手动,而左眼视力为6/6,同时右眼存在相对性传入瞳孔障碍。他的右眼视神经功能减退,眼前节无明显异常,眼底检查发现有樱桃红斑、黄斑苍白、上方弓形区呈箱格样改变,以及视盘下方视网膜血管化,视盘边缘模糊。左眼检查无明显异常。除视神经外,所有颅神经均完整。他被收入病房。在病房期间,他突然出现左侧上下肢无力和麻木,被诊断为急性缺血性中风。血液检查显示低密度脂蛋白胆固醇升高至3.51 mmol/L,抗核抗体(ANA)阳性,心电图显示窦性心律,无房颤。超声心动图正常,脑部计算机断层血管造影显示右眼动脉起始部和近端不显影,怀疑有血栓形成及远端再通,颈部和颅内其他动脉未发现血栓形成证据。患者开始每天服用150毫克阿司匹林和每晚服用20毫克阿托伐他汀;随后,他的视力略有改善。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e2e6/10914528/5edf0a4be391/cureus-0016-00000053577-i01.jpg

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