Kaba Conde, Salifou Morézik, Barry Abdoulaye, Adjakou Florent, Touré Moriba, Kamissoko Aly Badra, Cissé Fodé Abass
Department of Rheumatology, Ignace Deen University Hospital, Conakry, Guinea.
Department of Neurology, Ignace Deen University Hospital, Conakry, Guinea.
Tunis Med. 2023 Aug-Sep;101(8-9):680-683.
SpA is a group of chronic inflammatory rheumatic diseases that mainly affect the axial skeleton, but may also associate peripheral manifestations such as arthritis, enthesitis and dactylitis.
Describe the peripheral manifestations of SpA.
We conducted a descriptive cross-sectional study of SpA patients received at the rheumatology department of CHU Ignace Deen in Conakry over a one-year period from June 1, 2021 to May 31, 2022. The diagnosis of SpA was retained in accordance with the ASAS (Assessment of spondyloarthritis internationnal society) classification and data on peripheral manifestations were collected.
A total of 275 patients met the criteria and 82 had at least one peripheral involvement (29.8%). The mean age was 52.3 years, with females predominating in 58 (70.5%) cases. The mean time to diagnosis was 11 years. The most frequent peripheral manifestation was peripheral joint involvement (78%), followed by peripheral enthesitis (36.6%). The predominant clinical form was axial in 51.2%, with HLA-B27 antigen present in 63% and sacroiliitis in 51.2%. Treatment was based on NSAIDs (67.1%).
Peripheral manifestations are becoming increasingly frequent in SpA, and are dominated by peripheral joint involvement. The predominant clinical form was axial, with a strong association with HLA-B27.
脊柱关节炎(SpA)是一组慢性炎症性风湿性疾病,主要影响中轴骨骼,但也可能伴有外周表现,如关节炎、附着点炎和指(趾)炎。
描述脊柱关节炎的外周表现。
我们对2021年6月1日至2022年5月31日在科纳克里伊尼亚斯·德恩大学医院风湿病科就诊的脊柱关节炎患者进行了一项描述性横断面研究。根据国际脊柱关节炎评估协会(ASAS)分类确定脊柱关节炎的诊断,并收集外周表现的数据。
共有275例患者符合标准,82例(29.8%)至少有一处外周受累。平均年龄为52.3岁,女性占58例(70.5%)。平均诊断时间为11年。最常见的外周表现是外周关节受累(78%),其次是外周附着点炎(36.6%)。51.2%的主要临床类型为中轴型,63%存在HLA - B27抗原,51.2%存在骶髂关节炎。治疗以非甾体抗炎药为主(67.1%)。
外周表现在脊柱关节炎中越来越常见,以外周关节受累为主。主要临床类型为中轴型,与HLA - B27密切相关。