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肥胖的突尼斯成年人在袖状胃切除术前和术后的维生素状况。

Vitamin Status of Obese Tunisian adults before and after Sleeve Gastrectomy.

机构信息

Department A, National Institute of Nutrition and Food Technology of Tunis, Tunisia.

Research Obesity Unit of the National Institute of Nutrition and Food Technology of Tunis.

出版信息

Tunis Med. 2023 Aug-Sep;101(8-9):709-714.

Abstract

INTRODUCTION

The worldwide obesity epidemic continues unabated. Obesity and its associated health risks are considered as the major causes of morbidity and mortality. Currently, bariatric surgery is the most effective treatment for people with severe obesity resulting in sustainable weight loss and a reduced risk for co-morbidities. Sleeve gastrectomy is the most common bariatric procedure undertaken in Tunisia.

AIM

we aim to evaluate the vitamin status of the obese patients before and after sleeve gastrectomy.

METHODS

Thirty obese patients undergoing sleeve gastrectomy, were recruited from Obesity unit. In this study. A biological assessment was performed pre-operatively and controlled 6 months following the sleeve gastrectomy including: calcemia, parathyroid hormone (PTH), albuminemia and dosage of vitamin D, vitamin B9 and vitamin B12.

RESULTS

Six months post sleeve gastrectomy, vitamin deficiencies were more prevalent: the mean level of vitamin B9, vitamin B12 and vitamin D respectively, has decreased from 5.03±3.28 ng / ml to 2.71±1.52 ng / ml, from 348.06±158.92 pg/ml to 264.62±119.77 pg/ml and from 17.18±11.45 ng/ml to 11.69±8.22 ng/ml, with a statistically significant difference (p=0.008, p=0.01 and p=0.012). Sleeve gastrectomy has proven to be an effective weight loss treatment. However, nutritional deficiencies have worsened during postoperative period.

CONCLUSION

This study highlights the importance of early identification, appropriate treatment and prophylactic micronutrient supplementation.

摘要

简介

全球肥胖症流行仍在继续。肥胖症及其相关健康风险被认为是发病率和死亡率的主要原因。目前,减重手术是治疗严重肥胖症患者的最有效方法,可实现可持续的体重减轻和降低合并症的风险。袖状胃切除术是突尼斯最常见的减重手术。

目的

我们旨在评估袖状胃切除术前和术后肥胖患者的维生素状况。

方法

从肥胖症科招募了 30 名接受袖状胃切除术的肥胖患者。在这项研究中,在术前进行了生物学评估,并在袖状胃切除术后 6 个月进行了控制,包括血钙、甲状旁腺激素(PTH)、白蛋白和维生素 D、维生素 B9 和维生素 B12 的剂量。

结果

在袖状胃切除术后 6 个月,维生素缺乏更为普遍:维生素 B9、维生素 B12 和维生素 D 的平均水平分别从 5.03±3.28ng/ml 降至 2.71±1.52ng/ml,从 348.06±158.92pg/ml 降至 264.62±119.77pg/ml,从 17.18±11.45ng/ml 降至 11.69±8.22ng/ml,差异具有统计学意义(p=0.008,p=0.01 和 p=0.012)。袖状胃切除术已被证明是一种有效的减肥治疗方法。然而,术后营养缺乏状况恶化。

结论

本研究强调了早期识别、适当治疗和预防性补充微量营养素的重要性。

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