Suppr超能文献

致编辑的信:发作性停搏作为新发癫痫的首发症状的病例报告。

Lettre to editor: Case report of an ictal asystole as debut in new onset epilepsy.

机构信息

Neurology Department, Hospital Universitario Fundación Jiménez Díaz, Madrid, Spain.

出版信息

Neurol Sci. 2024 Jul;45(7):3529-3530. doi: 10.1007/s10072-024-07440-9. Epub 2024 Mar 6.

Abstract

The case report describes a 65-year-old man with arterial hypertension and a metallic aortic valve who presented to the emergency room for a loss of consciousness event and memory impairment. The electroencephalographic recording showed right temporal epileptiform activity followed by a 9 s asystole with quick consciousness recovery. The patient was diagnosed with right temporal epilepsy with asystole and was prescribed levetiracetam to prevent new events. A pacemaker was indicated in the follow-up for the long duration of the asystole, preventing major morbidity. Ictal asystole (IA) is a rare phenomenon of epilepsy that leads to syncope. It is observed in focal epilepsy, especially in left temporal epilepsy. Underlying cardiac pathology may facilitate IA, especially when the onset of the epilepsy is new. Knowledge of focal temporal semiology is key, concerning our case report, the memory impairment points to temporal pathology, and ictal vomiting in the non-dominant hemisphere. Anti-seizures drugs must be initiated in all patients, and there is a recommendation to avoid those with negative inotropic and arrhythmogenic effects (such as phenytoin, carbamazepine, and lacosamide). There is a discussion about pacemaker indication, however, it is highly recommended in non-controlled epilepsy and in ictal asystoles that last for more than 6 s to reduce morbidity.

摘要

这是一份关于 65 岁男性动脉高血压合并金属主动脉瓣的病例报告,他因意识丧失和记忆障碍而到急诊室就诊。脑电图记录显示右侧颞叶癫痫样活动,随后出现 9 秒的停搏,意识迅速恢复。患者被诊断为右侧颞叶癫痫伴停搏,并被开了左乙拉西坦以预防新的发作。由于停搏时间较长,后续需要安置起搏器,以防止严重的发病率。癫痫发作性停搏(IA)是一种罕见的癫痫现象,可导致晕厥。它发生在局灶性癫痫中,尤其是在左侧颞叶癫痫中。潜在的心脏病理学可能会促进 IA 的发生,尤其是当癫痫发作是新出现的时候。了解局灶性颞叶半侧发作的症状是关键,就我们的病例报告而言,记忆障碍指向颞叶病变,以及非优势半球的癫痫性呕吐。所有患者都必须开始使用抗癫痫药物,并且建议避免使用具有负性肌力和致心律失常作用的药物(如苯妥英钠、卡马西平、拉考酰胺)。关于起搏器的适应证存在争议,但在未控制的癫痫和持续超过 6 秒的癫痫性停搏中,强烈推荐使用起搏器,以降低发病率。

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验