• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

性别差异在为成年冠心病患者提供心脏药物治疗方面的影响:对德国萨克森-安哈尔特州 2018 至 2020 年医保报销数据的分析。

Sex differences in cardiologic medication provision for adults with coronary heart disease: an analysis of health claims data from 2018 to 2020 in Saxony-Anhalt, Germany.

机构信息

Martin-Luther-University Halle Wittenberg, Medical Faculty, Institute of Nursing and Health Science, Magdeburger Str. 8, 06108, Halle (Saale) , Germany.

AOK Sachsen-Anhalt, Magdeburg, Germany.

出版信息

BMC Health Serv Res. 2024 Mar 6;24(1):288. doi: 10.1186/s12913-024-10727-4.

DOI:10.1186/s12913-024-10727-4
PMID:38448928
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10916020/
Abstract

BACKGROUND

Coronary heart diseases (CHDs) have experienced the largest increase worldwide as a cause of death, accounting for 16% of all deaths. In Saxony-Anhalt, a federal state in Germany, both CHD morbidity and acute myocardial infarction mortality rates are particularly high. Several risk factors associated with CHDs have been studied in Saxony-Anhalt, but sex differences in service use and medication have not been investigated. This study therefore aimed to investigate sex differences in the quality and quantity of cardiological care provided to adults with CHD.

METHODS

This study used health claims data from 2018 to 2020 to analyse the utilisation of healthcare services and adherence to medication-related guideline recommendations in primary and specialist care. The sample included 133,661 individuals with CHD from a major statutory health insurance company (Germany).

RESULTS

Almost all CHD patients (> 99%) received continuous primary care. Continuous cardiologist utilisation was lower for females than for males, with 15.0% and 22.2%, respectively, and sporadic utilisation showed greater differences, with 33.5% of females and 43.4% of males seeking sporadic cardiologist consultations. Additionally, 43.1% of the identified CHD patients participated in disease management programmes (DMPs). The study also examined the impact of DMP participation and cardiologist care on medication uptake and revealed that sex differences in medication uptake, except for statin use, were mitigated by these factors. Statins were prescribed to 42.9% of the CHD patients eligible for statin prescription in accordance with the QiSA indicator for statin prescription eligibility. However, there were significant sex differences in statin utilisation. Female CHD patients were less likely to use statins (35.2%) than male CHD patients were (50.1%). The difference in statin utilisation persisted after adjustment for DMP participation and cardiologist consultation.

CONCLUSIONS

This study highlights sex differences in the utilisation of cardiological healthcare services for patients with CHD in the Saxony-Anhalt cohort. These findings underscore the continuing need for interventions to reduce sex inequalities in accessing healthcare and providing health care for patients with CHD. Factors at the health care system, patient, and physician levels should be further investigated to eventually improve statin prescription in people with CHD, especially women.

摘要

背景

冠心病(CHD)已成为全球范围内导致死亡的首要原因,占所有死亡人数的 16%。在德国萨克森-安哈尔特州,CHD 的发病率和急性心肌梗死死亡率尤其高。该州已经研究了与 CHD 相关的多个风险因素,但尚未研究性别差异对服务利用和药物治疗的影响。因此,本研究旨在调查萨克森-安哈尔特州成年 CHD 患者的心血管护理质量和数量的性别差异。

方法

本研究使用了 2018 年至 2020 年的健康索赔数据,分析了初级保健和专科保健中医疗服务的利用情况以及药物治疗相关指南建议的遵守情况。该样本包括一家主要法定健康保险公司(德国)的 133661 名 CHD 患者。

结果

几乎所有 CHD 患者(>99%)都接受了连续的初级保健。女性连续接受心脏病专家治疗的比例低于男性,分别为 15.0%和 22.2%,而偶发性利用的差异更大,女性中有 33.5%,男性中有 43.4%寻求偶发性心脏病专家咨询。此外,43.1%的确定为 CHD 的患者参加了疾病管理计划(DMP)。本研究还检查了 DMP 参与和心脏病专家护理对药物使用的影响,结果表明,除他汀类药物使用外,这些因素减轻了药物使用方面的性别差异。根据他汀类药物使用资格的 QiSA 指标,符合他汀类药物使用资格的 CHD 患者中有 42.9%接受了他汀类药物治疗。然而,在他汀类药物使用方面存在显著的性别差异。女性 CHD 患者使用他汀类药物的比例(35.2%)低于男性(50.1%)。在调整了 DMP 参与和心脏病专家咨询后,他汀类药物使用的差异仍然存在。

结论

本研究强调了萨克森-安哈尔特队列中 CHD 患者心血管医疗服务利用方面的性别差异。这些发现强调了需要继续采取干预措施,以减少获得医疗保健方面的性别不平等,并为 CHD 患者提供医疗保健。还应进一步研究医疗保健系统、患者和医生层面的因素,最终改善 CHD 患者,尤其是女性患者的他汀类药物处方。

相似文献

1
Sex differences in cardiologic medication provision for adults with coronary heart disease: an analysis of health claims data from 2018 to 2020 in Saxony-Anhalt, Germany.性别差异在为成年冠心病患者提供心脏药物治疗方面的影响:对德国萨克森-安哈尔特州 2018 至 2020 年医保报销数据的分析。
BMC Health Serv Res. 2024 Mar 6;24(1):288. doi: 10.1186/s12913-024-10727-4.
2
Adherence To Lipid-Lowering Therapy In Patients With Coronary Heart Disease From The State Of Saxony-Anhalt, Germany.德国萨克森-安哈尔特州冠心病患者对降脂治疗的依从性
Vasc Health Risk Manag. 2019 Oct 31;15:477-483. doi: 10.2147/VHRM.S197089. eCollection 2019.
3
The regional myocardial infarction registry of Saxony-Anhalt (RHESA) in Germany - rational and study protocol.德国萨克森-安哈尔特州的区域性心肌梗死登记处(RHESA)——原理与研究方案。
BMC Cardiovasc Disord. 2015 Jun 9;15:45. doi: 10.1186/s12872-015-0040-2.
4
Initiation of statins after hospitalization for coronary heart disease.冠心病住院后开始使用他汀类药物。
J Manag Care Pharm. 2007 Jun;13(5):385-96. doi: 10.18553/jmcp.2007.13.5.385.
5
A systematic review and economic evaluation of statins for the prevention of coronary events.他汀类药物预防冠状动脉事件的系统评价与经济学评估
Health Technol Assess. 2007 Apr;11(14):1-160, iii-iv. doi: 10.3310/hta11140.
6
Association between copayment and adherence to statin treatment initiated after coronary heart disease hospitalization: a longitudinal, retrospective, cohort study.冠心病住院后启动的他汀类药物治疗的自付费用与依从性之间的关联:一项纵向、回顾性队列研究。
Clin Ther. 2007 Dec;29(12):2748-57. doi: 10.1016/j.clinthera.2007.12.022.
7
Lipid lowering drug therapy in patients with coronary heart disease from 24 European countries--Findings from the EUROASPIRE IV survey.来自24个欧洲国家的冠心病患者的降脂药物治疗——EUROASPIRE IV调查结果
Atherosclerosis. 2016 Mar;246:243-50. doi: 10.1016/j.atherosclerosis.2016.01.018. Epub 2016 Jan 13.
8
[Changes in the prevalence of statin use in Germany - findings from national health interview and examination surveys 1997-1999 and 2008-2011].[德国他汀类药物使用流行率的变化——1997 - 1999年和2008 - 2011年全国健康访谈与检查调查结果]
Z Evid Fortbild Qual Gesundhwes. 2017 May;122:22-31. doi: 10.1016/j.zefq.2017.04.001. Epub 2017 May 13.
9
Comparative Effectiveness of Combination Therapy with Statins and Angiotensin-Converting Enzyme Inhibitors versus Angiotensin II Receptor Blockers in Patients with Coronary Heart Disease: A Nationwide Population-Based Cohort Study in Korea.比较冠心病患者联合使用他汀类药物和血管紧张素转换酶抑制剂与血管紧张素 II 受体阻滞剂的疗效:来自韩国的一项全国性基于人群的队列研究。
Pharmacotherapy. 2018 Nov;38(11):1095-1105. doi: 10.1002/phar.2181. Epub 2018 Oct 21.
10
Assessment of Trends in Statin Therapy for Secondary Prevention of Atherosclerotic Cardiovascular Disease in US Adults From 2007 to 2016.评估 2007 年至 2016 年美国成年人中他汀类药物用于动脉粥样硬化性心血管疾病二级预防的趋势。
JAMA Netw Open. 2020 Nov 2;3(11):e2025505. doi: 10.1001/jamanetworkopen.2020.25505.

引用本文的文献

1
Teaching gender medicine can enhance the quality of healthcare.教授性别医学可以提高医疗保健质量。
Am Heart J Plus. 2024 Jun 25;44:100418. doi: 10.1016/j.ahjo.2024.100418. eCollection 2024 Aug.

本文引用的文献

1
Associations between statins and adverse events in secondary prevention of cardiovascular disease: Pairwise, network, and dose-response meta-analyses of 47 randomized controlled trials.他汀类药物与心血管疾病二级预防中不良事件的关联:47项随机对照试验的成对、网状和剂量反应荟萃分析。
Front Cardiovasc Med. 2022 Aug 25;9:929020. doi: 10.3389/fcvm.2022.929020. eCollection 2022.
2
Gender Differences in Guideline-Directed Medical Therapy for Cardiovascular Disease Among Young Veterans.青年退伍军人心血管疾病指南指导下的药物治疗的性别差异。
J Gen Intern Med. 2022 Sep;37(Suppl 3):806-815. doi: 10.1007/s11606-022-07595-1. Epub 2022 Aug 30.
3
Trends in Lipid Concentrations and Lipid Control Among US Adults, 2007-2018.2007-2018 年美国成年人血脂浓度和血脂控制趋势。
JAMA. 2022 Aug 23;328(8):737-745. doi: 10.1001/jama.2022.12567.
4
Disparities in the Prescription of Statins in the Primary Care Setting: A Retrospective Observational Study.初级保健环境中他汀类药物处方的差异:一项回顾性观察研究。
Curr Probl Cardiol. 2022 Nov;47(11):101329. doi: 10.1016/j.cpcardiol.2022.101329. Epub 2022 Jul 20.
5
Utilisation of outpatient medical services in Germany - Results from GEDA 2019/2020-EHIS.德国门诊医疗服务的利用情况——2019/2020年德国健康访谈与疾病调查(GEDA)-欧洲健康访谈调查(EHIS)的结果
J Health Monit. 2021 Sep 15;6(3):45-65. doi: 10.25646/8555. eCollection 2021 Sep.
6
Cardiovascular Outcomes and Mortality Associated With Discontinuing Statins in Older Patients Receiving Polypharmacy.接受多药治疗的老年患者停用他汀类药物与心血管结局和死亡率的关系。
JAMA Netw Open. 2021 Jun 1;4(6):e2113186. doi: 10.1001/jamanetworkopen.2021.13186.
7
The Lancet women and cardiovascular disease Commission: reducing the global burden by 2030.柳叶刀妇女与心血管疾病委员会:到 2030 年降低全球负担。
Lancet. 2021 Jun 19;397(10292):2385-2438. doi: 10.1016/S0140-6736(21)00684-X. Epub 2021 May 16.
8
Gender gap in risk factor control of coronary patients far from closing: results from the European Society of Cardiology EUROASPIRE V registry.冠心病患者危险因素控制的性别差距远未缩小:来自欧洲心脏病学会 EUROASPIRE V 注册研究的结果。
Eur J Prev Cardiol. 2022 Mar 11;29(2):344-351. doi: 10.1093/eurjpc/zwaa144.
9
[Social inequalities in healthcare provision for patients with coronary heart disease: Results from the GEDA (German Health Update) study 2014/2015].[冠心病患者医疗保健服务中的社会不平等:2014/2015年德国健康更新(GEDA)研究结果]
Z Evid Fortbild Qual Gesundhwes. 2021 Feb;160:48-54. doi: 10.1016/j.zefq.2020.11.009. Epub 2021 Jan 13.
10
Participation in disease management programs and major adverse cardiac events in patients after acute myocardial infarction: a longitudinal study based on registry data.参与疾病管理计划与急性心肌梗死后患者主要不良心脏事件:基于注册数据的纵向研究。
BMC Cardiovasc Disord. 2021 Jan 6;21(1):18. doi: 10.1186/s12872-020-01832-3.