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病例报告与文献综述:电热毯过热导致急性横纹肌溶解症并发吉兰-巴雷综合征

Case report and literature review: Acute rhabdomyolysis caused by overheating of electric blanket complicated with Guillain-Barré syndrome.

作者信息

Jiang Dongyang, Zhao Ming, Li Xiaojun, Hu Qiongdan, Zhang Qiong

机构信息

Department of Nephrology, The Affiliated Traditional Chinese Medicine Hospital, Southwest Medical University, Luzhou, China.

Institute of Integrated Chinese and Western Medicine, Southwest Medical University, Luzhou, Sichuan, China.

出版信息

Front Neurol. 2024 Feb 21;15:1362648. doi: 10.3389/fneur.2024.1362648. eCollection 2024.

DOI:10.3389/fneur.2024.1362648
PMID:38450069
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10915280/
Abstract

Rhabdomyolysis (RM) induced by electric blankets is exceedingly rare, with only three cases identified in our literature review. Both RM and Guillain-Barré syndrome (GBS) present with similar clinical manifestations of myalgia and muscle weakness, posing a potential challenge for accurate diagnosis in clinical settings. This report presents the case of a 22-year-old man who developed RM subsequent to the use of an electric blanket. Despite undergoing plasma exchange and renal replacement therapy, the patient continued to exhibit poor muscle strength in both lower limbs. Subsequent comprehensive evaluation revealed the presence of concurrent GBS. Following a 5-day course of intravenous gamma globulin treatment, the patient experienced rapid recovery of muscle strength and was discharged. Additionally, we reviewed seven cases from the literature of coexistent RM and GBS. This indicated that investigation of the timing of onset of muscle strength decline in RM patients could help to identify potential concurrent neurological or muscular disorders. In cases in which concurrent GBS and RM cannot be definitively ascertained during early hospitalization, prioritizing plasma exchange treatment may lead to improved patient outcomes.

摘要

电热毯诱发的横纹肌溶解症(RM)极为罕见,在我们的文献综述中仅发现3例。RM和吉兰-巴雷综合征(GBS)都表现出类似的肌痛和肌肉无力的临床表现,这给临床环境中的准确诊断带来了潜在挑战。本报告介绍了一名22岁男性在使用电热毯后发生RM的病例。尽管接受了血浆置换和肾脏替代治疗,但患者双下肢肌肉力量仍持续较差。随后的综合评估发现同时存在GBS。经过5天的静脉注射丙种球蛋白治疗,患者肌肉力量迅速恢复并出院。此外,我们还回顾了文献中7例RM和GBS共存的病例。这表明,调查RM患者肌肉力量下降的发病时间有助于识别潜在的并发神经或肌肉疾病。在早期住院期间无法明确确定GBS和RM并发的情况下,优先进行血浆置换治疗可能会改善患者的预后。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e6a6/10915280/16ea08c76652/fneur-15-1362648-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e6a6/10915280/16ea08c76652/fneur-15-1362648-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e6a6/10915280/16ea08c76652/fneur-15-1362648-g001.jpg

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本文引用的文献

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Guillain-Barré syndrome (GBS) complicated by rhabdomyolysis (RML): Case reports of 2 children and literature review.吉兰-巴雷综合征(GBS)合并横纹肌溶解症(RML):2例儿童病例报告及文献综述
Front Pediatr. 2022 Oct 10;10:1001775. doi: 10.3389/fped.2022.1001775. eCollection 2022.
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BMC Neurol. 2020 May 27;20(1):214. doi: 10.1186/s12883-020-01796-z.
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Serum Aminotransferase Level in Rhabdomyolysis according to Concurrent Liver Disease.横纹肌溶解症患者血清转氨酶水平与合并肝病的关系
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Heatstroke.中暑
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