农村社区老年人肌少症 6 种筛查方法的比较：一项诊断准确性研究。
Comparison of six screening methods for sarcopenia among rural community-dwelling older adults: a diagnostic accuracy study.
机构信息
School of Public Health, Southwest Medical University, Sichuan, Luzhou, China.
Collaborating Center of the National Institute of Health Data Sciences of China, Southwest Medical University, Sichuan, Luzhou, China.
出版信息
Eur Geriatr Med. 2024 Jun;15(3):681-688. doi: 10.1007/s41999-024-00955-6. Epub 2024 Mar 7.
OBJECTIVE
The objective of this analysis was to determine the diagnostic efficacy of the Ishii test, SarSA-Mod, SARC-F, SARC-Calf, SARC-F+AC, and SARC-Calf+AC for screening for sarcopenia among rural community-dwelling older adults.
METHODS
The AWGS 2019 diagnostic criteria was a diagnostic reference for sarcopenia. There were six screening tools whose accuracy was determined through the use of metrics, including specificity, sensitivity, negative and positive predictive values, and the receiver operating characteristic (ROC) curve.
RESULTS
The study included 551 participants (304 women, age 70.9 ± 4.9 years). The prevalence of sarcopenia was 44.5% in men and 39.1% in women. In males, the sensitivity/specificity of the Ishii test, SarSA-Mod, SARC-F, SARC-Calf, SARC-F+AC, and SARC-Calf+AC screening sarcopenia were 87.3%/65.7%, 98.2%/21.9%, 6.4%/98.5%, 28.2%/91.2%, 33.6%/83.9%, and 84.6%/43.8%, and in females, they were 68.1%/82.2, 100%/23.2%, 16.0%/90.3%, 35.3%/84.3%, 58.8%/61.1%, and 89.9%/42.2%, respectively. In males, the area under the curves of the Ishii test, SarSA-Mod, SARC-F, SARC-Calf, SARC-F+AC, and SARC-Calf+AC were 0.846 (95% CI 0.795-0.889), 0.800 (95% CI 0.745-0.848), 0.581 (95% CI 0.516-0.643), 0.706 (95% CI 0.645-0.762), 0.612 (95% CI 0.548-0.673), and 0.707 (95% CI 0.646-0.763), respectively, and in females, they were 0.824 (95% CI 0.776-0.865), 0.845 (95% CI 0.799-0.883), 0.581 (95% CI 0.524-0.637), 0.720 (95% CI 0.666-0.770), 0.632 (95% CI 0.575-0.686), and 0.715 (95% CI 0.661-0.765), respectively.
CONCLUSION
Our findings demonstrate that the overall accuracy of the Ishii test was best among the six screening tools for sarcopenia screening in rural community-dwelling older adults.
目的
本分析的目的是确定 Ishii 试验、SarSA-Mod、SARC-F、SARC-Calf、SARC-F+AC 和 SARC-Calf+AC 用于筛查农村社区居住的老年人群中肌少症的诊断效能。
方法
2019 年 AWGS 诊断标准是肌少症的诊断参考。有六种筛查工具，通过使用包括特异性、敏感性、阴性和阳性预测值以及接收者操作特征（ROC）曲线在内的指标来确定其准确性。
结果
本研究纳入了 551 名参与者（304 名女性，年龄 70.9±4.9 岁）。男性肌少症的患病率为 44.5%，女性为 39.1%。在男性中，Ishii 试验、SarSA-Mod、SARC-F、SARC-Calf、SARC-F+AC 和 SARC-Calf+AC 筛查肌少症的灵敏度/特异性分别为 87.3%/65.7%、98.2%/21.9%、6.4%/98.5%、28.2%/91.2%、33.6%/83.9%和 84.6%/43.8%，在女性中分别为 68.1%/82.2%、100%/23.2%、16.0%/90.3%、35.3%/84.3%、58.8%/61.1%和 89.9%/42.2%。在男性中，Ishii 试验、SarSA-Mod、SARC-F、SARC-Calf、SARC-F+AC 和 SARC-Calf+AC 的曲线下面积分别为 0.846（95%CI 0.795-0.889）、0.800（95%CI 0.745-0.848）、0.581（95%CI 0.516-0.643）、0.706（95%CI 0.645-0.762）、0.612（95%CI 0.548-0.673）和 0.707（95%CI 0.646-0.763），在女性中分别为 0.824（95%CI 0.776-0.865）、0.845（95%CI 0.799-0.883）、0.581（95%CI 0.524-0.637）、0.720（95%CI 0.666-0.770）、0.632（95%CI 0.575-0.686）和 0.715（95%CI 0.661-0.765）。
结论
我们的研究结果表明，在用于农村社区居住的老年人群肌少症筛查的六种筛查工具中，Ishii 试验的整体准确性最高。
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