VIRTU Research Group, Copenhagen Research Center for Mental Health, Mental Health Center Copenhagen, Copenhagen University Hospital, Denmark; Department of Clinical Medicine (DK), University of Copenhagen, Denmark.
VIRTU Research Group, Copenhagen Research Center for Mental Health, Mental Health Center Copenhagen, Copenhagen University Hospital, Denmark.
Psychiatry Res. 2024 Apr;334:115834. doi: 10.1016/j.psychres.2024.115834. Epub 2024 Mar 1.
A large group of psychiatric patients suffer from auditory hallucinations (AH) despite relevant treatment regimens. In mental health populations, AH tend to be verbal (AVH) and the content critical or abusive. Trials employing immersive virtual reality (VR) to treat mental health disorders are emerging.
The aim of this scoping review is to provide an overview of clinical trials utilizing VR in the treatment of AH and to document knowledge gaps in the literature.
PubMed, Cochrane Library, and Embase were searched for studies reporting on the use of VR to target AH.
16 papers were included in this PRISMA scoping review (ScR). In most studies VR therapy (VRT) was employed to ameliorate treatment resistant AVH in schizophrenia spectrum disorders. Only two studies included patients with a diagnosis of affective disorders. The VRT was carried out with the use of an avatar to represent the patient's most dominant voice.
The research field employing VR to treat AH is promising but still in its infancy. Results from larger randomized clinical trials are needed to establish substantial evidence of therapy effectiveness. Additionally, the knowledge base would benefit from more profound qualitative data exploring views of patients and therapists.
尽管采用了相关的治疗方案，但仍有大量精神病患者患有听觉幻觉（AH）。在精神卫生人群中，AH 往往是言语性的（AVH），内容具有批判性或辱骂性。采用沉浸式虚拟现实（VR）治疗心理健康障碍的试验正在出现。
本范围综述旨在概述临床研究中使用 VR 治疗 AH 的情况，并记录文献中的知识空白。
在 PubMed、Cochrane Library 和 Embase 中搜索了报告使用 VR 治疗 AH 的研究。
这项 PRISMA 范围综述（ScR）共纳入了 16 篇论文。在大多数研究中，VR 治疗（VRT）被用于改善精神分裂症谱系障碍患者的难治性 AVH。只有两项研究纳入了情感障碍诊断的患者。VRT 使用代表患者最主要声音的化身进行。
使用 VR 治疗 AH 的研究领域很有前途，但仍处于起步阶段。需要更大规模的随机临床试验结果来建立治疗效果的实质性证据。此外，更深入的探索患者和治疗师观点的定性数据将使知识库受益。
