Suppr超能文献

小儿肥胖与阴茎和睾丸发育。

Pediatric obesity and development of the penis and testis.

机构信息

Department of Urology, Pusan National University Yangsan Hospital, Yangsan, Korea.

Department of Urology, Pusan National University School of Medicine, Yangsan, Korea.

出版信息

Investig Clin Urol. 2024 Mar;65(2):189-195. doi: 10.4111/icu.20230287.

Abstract

PURPOSE

Pediatric obesity is increasing in many countries as socioeconomic status improves and the consumption of high calorie food increases. Thus, effect of obesity on genital development is an important topic. This study aimed to determine relationships of body mass index (BMI) with penile parameters and testicular volume in pediatric patients without penile or testicular abnormalities.

MATERIALS AND METHODS

Data from 1,499 male pediatric patients from our center were analyzed. Patients with penile or testicular abnormalities were excluded. Their age ranged from 2 to 18 years. These patients were divided into two groups based on their BMI: normal BMI (5th-85th percentile) and high BMI (≥85th percentile). Factors used in analysis included age, anthropometric indicators, baseline penile length (BPL), stretched penile length (SPL), penile circumference (PC), and mean testicular volume. These same parameters were analyzed for different age groups.

RESULTS

Pediatric patients with normal BMI showed longer BPL and SPL than patients with high BMI (p<0.05). However, PC and mean testicular volumes showed no significant difference between the two groups. BPL was significantly longer in the normal BMI group starting at ten years of age. SPL was significantly longer in the normal BMI group starting at eleven years of age.

CONCLUSIONS

Our study confirms that having a higher BMI during childhood has a negative effect on penile length. However, there was no significant relationship between BMI and PC or testicular volume.

摘要

目的

随着社会经济地位的提高和高热量食物消费的增加,许多国家的儿童肥胖症正在增加。因此,肥胖对生殖器发育的影响是一个重要的课题。本研究旨在确定体重指数(BMI)与生殖器参数和睾丸体积在无阴茎或睾丸异常的儿科患者中的关系。

材料和方法

分析了来自我们中心的 1499 名男性儿科患者的数据。排除了有阴茎或睾丸异常的患者。他们的年龄从 2 岁到 18 岁不等。这些患者根据 BMI 分为两组:正常 BMI(第 5-85 百分位)和高 BMI(≥第 85 百分位)。分析中使用的因素包括年龄、人体测量指标、基础阴茎长度(BPL)、伸展阴茎长度(SPL)、阴茎周长(PC)和平均睾丸体积。对不同年龄组进行了相同的参数分析。

结果

正常 BMI 的儿科患者的 BPL 和 SPL 比高 BMI 患者长(p<0.05)。然而,两组之间的 PC 和平均睾丸体积没有显著差异。正常 BMI 组从十岁开始 BPL 明显更长。正常 BMI 组从 11 岁开始 SPL 明显更长。

结论

我们的研究证实,儿童时期 BMI 较高对阴茎长度有负面影响。然而,BMI 与 PC 或睾丸体积之间没有显著关系。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0e76/10925733/7a0b3c0fb78b/icu-65-189-g001.jpg

相似文献

1
Pediatric obesity and development of the penis and testis.
Investig Clin Urol. 2024 Mar;65(2):189-195. doi: 10.4111/icu.20230287.
3
Penile length-somatometric parameters relationship in healthy Egyptian men.
Andrologia. 2015 May;47(4):402-6. doi: 10.1111/and.12275. Epub 2014 Apr 2.
4
Concealed index for concealed penis in prepubertal children.
Investig Clin Urol. 2021 Mar;62(2):217-223. doi: 10.4111/icu.20200401.
5
Anthropometric, penile and testis measures in post-pubertal Italian males.
J Endocrinol Invest. 2013 May;36(5):287-92. doi: 10.3275/8514. Epub 2012 Jul 9.
7
Penile length and circumference: are they related to nose size?
Transl Androl Urol. 2023 May 31;12(5):708-714. doi: 10.21037/tau-22-869. Epub 2023 May 9.
8
Penile and Testicular Measurements in Male Neonates and Infants: Single Center Egyptian Study.
Endocr Metab Immune Disord Drug Targets. 2017 Nov 16;17(4):309-316. doi: 10.2174/1871530317666170912152351.
9
Stretched penile length and anogenital distance in Egyptian boys aged one month to five years.
J Pediatr Urol. 2021 Feb;17(1):110.e1-110.e7. doi: 10.1016/j.jpurol.2020.11.007. Epub 2020 Nov 6.
10
Size of external genital organs and somatometric parameters among physically normal men younger than 40 years old.
Urology. 2002 Sep;60(3):485-9; discussion 490-1. doi: 10.1016/s0090-4295(02)01869-1.

本文引用的文献

1
Obesity Is Strongly Associated With Low Testosterone and Reduced Penis Growth During Development.
J Clin Endocrinol Metab. 2021 Oct 21;106(11):3151-3159. doi: 10.1210/clinem/dgab535.
3
Concealed index for concealed penis in prepubertal children.
Investig Clin Urol. 2021 Mar;62(2):217-223. doi: 10.4111/icu.20200401.
4
Total and Central Adiposity Are Associated With Age at Gonadarche and Incidence of Precocious Gonadarche in Boys.
J Clin Endocrinol Metab. 2021 Apr 23;106(5):1352-1361. doi: 10.1210/clinem/dgab064.
5
Secular Trends in Pediatric Overweight and Obesity in Korea.
J Obes Metab Syndr. 2020 Mar 30;29(1):12-17. doi: 10.7570/jomes20002.
6
The Dynamic Transcriptional Cell Atlas of Testis Development during Human Puberty.
Cell Stem Cell. 2020 Feb 6;26(2):262-276.e4. doi: 10.1016/j.stem.2019.12.005. Epub 2020 Jan 9.
7
The 2017 Korean National Growth Charts for children and adolescents: development, improvement, and prospects.
Korean J Pediatr. 2018 May;61(5):135-149. doi: 10.3345/kjp.2018.61.5.135. Epub 2018 May 28.
9
Testicular growth and development in puberty.
Curr Opin Endocrinol Diabetes Obes. 2017 Jun;24(3):215-224. doi: 10.1097/MED.0000000000000339.
10
Obesity prevention and obesogenic behavior interventions in child care: A systematic review.
Prev Med. 2016 Jun;87:57-69. doi: 10.1016/j.ypmed.2016.02.016. Epub 2016 Feb 12.

文献AI研究员

20分钟写一篇综述,助力文献阅读效率提升50倍。

立即体验

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

马上搜索

文档翻译

学术文献翻译模型,支持多种主流文档格式。

立即体验