Department of Cardiothoracic and Vascular Surgery, Careggi University Teaching Hospital, University of Florence, Florence, Italy -
Department of Cardiothoracic and Vascular Surgery, Careggi University Teaching Hospital, University of Florence, Florence, Italy.
Int Angiol. 2024 Apr;43(2):262-270. doi: 10.23736/S0392-9590.24.05134-4. Epub 2024 Mar 8.
To estimate the impact of anesthetic conduct, alone and in combination with the type of femoral access, on early results after endovascular aneurysm repair (EVAR).
A retrospective multicenter analysis on patients undergoing elective standard EVAR at four academic centers was performed. Patients undergoing the procedure through either local or general anesthesia were compared. Comparative subanalyses of the two groups were performed for the type of femoral access to evaluate further impact on outcomes.
Five hundred twenty-four patients underwent elective standard EVAR, of which 207 (39.5%) under general anesthesia and 317 (60.5%) under local anesthesia. Patients who underwent general anesthesia had higher 30-day mortality rates (3.4% vs. 0.3%, P=0.005), as well as slightly worse 30-day major systemic complication rates (8.2% vs. 5.4%, P=0.195). There were no differences in terms of reinterventions (2.1% vs. 2.5%, P=0.768) and aneurysm-related mortality (0% vs. 0.4%, P=0.422) at one year. Total intervention times were significantly longer in the general anesthesia group (126 vs. 89 minutes, P=0.001), as well as the total length of hospital stay (7.6 vs. 5.3 days, P=0.007). At subanalyses, the combination of local anesthesia with bilateral percutaneous femoral access further improved 30-day outcomes and determined an additional reduction in total intervention times and ICU stays.
EVAR performed under local anesthesia has a significantly better impact on early results when compared to general anesthesia. Combining percutaneous bilateral femoral access to local anesthesia reduced procedural times, ICU stays and consequently improved early results.
评估麻醉管理以及与股动脉入路类型的组合对血管内动脉瘤修复(EVAR)后早期结果的影响。
对四家学术中心进行的择期标准 EVAR 患者进行回顾性多中心分析。比较了接受局部或全身麻醉的患者。对两组患者进行股动脉入路的比较亚分析,以进一步评估对结果的影响。
524 例患者接受择期标准 EVAR,其中 207 例(39.5%)接受全身麻醉,317 例(60.5%)接受局部麻醉。全身麻醉患者的 30 天死亡率较高(3.4%比 0.3%,P=0.005),30 天主要全身并发症发生率也略高(8.2%比 5.4%,P=0.195)。在一年时,再干预率(2.1%比 2.5%,P=0.768)和与动脉瘤相关的死亡率(0%比 0.4%,P=0.422)无差异。全身麻醉组的总干预时间明显较长(126 比 89 分钟,P=0.001),总住院时间也较长(7.6 比 5.3 天,P=0.007)。在亚分析中,局部麻醉联合双侧经皮股动脉入路进一步改善了 30 天的结果,并进一步减少了总干预时间和 ICU 停留时间。
与全身麻醉相比,局部麻醉进行的 EVAR 对早期结果的影响明显更好。将经皮双侧股动脉入路与局部麻醉相结合,可减少手术时间、ICU 停留时间,从而改善早期结果。