Fadah Kahtan, Khalafi Seyed, Corey Miller, Sotelo Jose, Farag Ahmed, Siddiqui Tariq, Abolbashari Mehran
Division of Cardiology, Department of Internal Medicine, Texas Tech University Health Sciences Center, 4800 Alberta Avenue, El Paso, TX 79905, USA.
Paul L. Foster School of Medicine, Texas Tech University Health Sciences Center, 5001 El Paso Drive, El Paso, TX 79905, USA.
Cardiol Res Pract. 2024 Feb 29;2024:4217162. doi: 10.1155/2024/4217162. eCollection 2024.
Patients with severe calcific native aortic valve stenosis (AS) who require valve replacement have two options, surgical aortic valve replacement (SAVR) or transcatheter aortic valve replacement (TAVR). TAVR was approved in late 2011 for extremely high-risk patients and was subsequently approved for high-risk (2012), intermediate-risk (2016), and low-risk (2019) patients. In 2019, TAVR procedures surpassed SAVR procedures for the first time in the United States. The approach to anesthesia for this procedure has also evolved. Initially, general anesthesia (GA) was preferred, but currently, conscious sedation (CS) is favored. This review aims to clarify the indications and contraindications for both approaches, as well as the advantages of one approach over the other. Recent studies show that conscious sedation has better outcomes in terms of all-cause mortality, procedure complications such as stroke, myocardial infarction, infection requiring antibiotics, acute kidney injury, and the need for inotropes or vasopressors.
需要进行瓣膜置换的严重钙化性主动脉瓣狭窄(AS)患者有两种选择,即外科主动脉瓣置换术(SAVR)或经导管主动脉瓣置换术(TAVR)。TAVR于2011年末被批准用于极高风险患者,随后又被批准用于高风险(2012年)、中风险(2016年)和低风险(2019年)患者。2019年,在美国TAVR手术首次超过了SAVR手术。该手术的麻醉方法也有所发展。最初,全身麻醉(GA)是首选,但目前,清醒镇静(CS)更受青睐。本综述旨在阐明两种方法的适应症和禁忌症,以及一种方法相对于另一种方法的优势。最近的研究表明,在全因死亡率、手术并发症如中风、心肌梗死、需要使用抗生素治疗的感染、急性肾损伤以及使用血管活性药物方面,清醒镇静有更好的结果。