Tassew Worku Chekol, Assefa Getaw Wubie, Zeleke Agerie Mengistie, Ferede Yeshiwas Ayal
Department of Medical Nursing, Teda Health Science College, Gondar, Ethiopia.
Department of CTID & HIV Medicine, Teda Health Science College, Gondar, Ethiopia.
Metabol Open. 2024 Feb 23;21:100280. doi: 10.1016/j.metop.2024.100280. eCollection 2024 Mar.
Complementary use of medicinal plants with prescribed drugs is becoming more widespread concern among people with chronic disease like cancer, HIV/AIDS, diabetes and hypertension. Consequently, the purpose of this review was to determine the prevalence and associated factors of herbal medicine use among patients suffering from chronic disease.
This systematic review and meta-analysis was conducted by searching articles from Cochrane library, Google scholar, PubMed and African journal online. Data was extracted using Microsoft excel format and imported in to Stata software version 11 (Stata Corp LLC, TX, USA) for analysis. Statistical heterogeneity across the studies was investigated using Cochran's Q chi-square test at the significance level of <0.05 and the I index. A random-effects model was used to estimate the pooled prevalence of herbal medicine use.
Our systematic search yielded a total of 17,665 records from four databases (Google scholar (12,800), PubMed (3835), Cochrane library (30) and African journal online (12). The pooled estimate of herbal medicine use among patients with chronic disease in Ethiopia is found to be 56.94% (95% CI: 49.75, 64.12, P < 0.001). Being female (POR = 2.06, 95% CI = 1.55, 2.75, I = 10.0%), rural residence (POR = 2.80, 95% CI = 1.42, 5.52, I = 89.1%), duration of the disease greater than 5 years (POR = 6.42, 95% CI = 4.188, 9.84, I = 48.3%) and having complication (POR = 4.65, 95% CI = 3.75, 5.77, I = 0.0%) were factors associated with herbal medicine use among patients living with chronic disease.
The study found a high prevalence of herbal medicine use among patients living with chronic disease. Being female, rural residence, duration of disease greater than 5 years and having complication were factors that are significantly associated with herbal medicine use. The prevalence of herbal medicine use among persons with chronic disease in Ethiopia presents significant implications for healthcare practice. Healthcare professionals need to adopt a patient-centered strategy that promotes open, judgment-free discussions about herbal medicine usage.
CRD42024498817.
在癌症、艾滋病毒/艾滋病、糖尿病和高血压等慢性病患者中，药用植物与处方药的互补使用正日益受到广泛关注。因此，本综述的目的是确定慢性病患者使用草药的患病率及相关因素。
通过检索考克兰图书馆、谷歌学术、PubMed和非洲在线期刊上的文章进行了这项系统综述和荟萃分析。数据以Microsoft excel格式提取，并导入到Stata软件版本11（美国德克萨斯州Stata公司有限责任公司）进行分析。使用Cochran's Q卡方检验在显著性水平<0.05和I指数下研究各研究之间的统计异质性。采用随机效应模型估计草药使用的合并患病率。
我们的系统检索共从四个数据库（谷歌学术（12800条）、PubMed（3835条）、考克兰图书馆（30条）和非洲在线期刊（12条））中获得了17665条记录。埃塞俄比亚慢性病患者中使用草药的合并估计患病率为56.94%（95%置信区间：49.75，64.12，P<0.001）。女性（比值比=2.06，95%置信区间=1.55，2.75，I=10.0%）、农村居民（比值比=2.80，95%置信区间=1.42，5.52，I=89.1%）、病程大于5年（比值比=6.42，95%置信区间=4.188，9.84，I=48.3%）和有并发症（比值比=4.65，95%置信区间=3.75，5.77，I=0.0%）是慢性病患者使用草药的相关因素。
该研究发现慢性病患者中使用草药的患病率很高。女性、农村居民、病程大于5年和有并发症是与使用草药显著相关的因素。埃塞俄比亚慢性病患者中使用草药的患病率对医疗实践具有重要意义。医疗保健专业人员需要采取以患者为中心的策略，促进关于草药使用的开放、无偏见的讨论。
PROSPERO注册编号：CRD42024498817。
