• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

评估印度尼西亚预防母婴传播艾滋病毒、梅毒和乙型肝炎三联消除计划的影响。

Evaluating the impact of triple elimination program for mother-to-child transmission of HIV, syphilis, and hepatitis B in Indonesia.

作者信息

Azhali Buti A, Setiabudi Djatnika, Alam Anggraini

机构信息

Department of Child Health, Faculty of Medicine, Universitas Islam Bandung, Bandung, Indonesia.

Department of Child Health, Faculty of Medicine, Universitas Padjadjaran, Bandung, Indonesia.

出版信息

Narra J. 2023 Dec;3(3):e405. doi: 10.52225/narra.v3i3.405. Epub 2023 Nov 17.

DOI:10.52225/narra.v3i3.405
PMID:38455604
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10919734/
Abstract

Indonesian government launched a triple elimination program to eliminate mother-to-child transmission (MTCT) of human immunodeficiency virus (HIV), syphilis, and hepatitis B in 2018, aiming to increase screening uptake among pregnant women during antenatal visits and to reduce the rates of these infections in children less than 50 per 100,000 live births. Despite this initiative, a thorough assessment of its effectiveness, particularly in Bandung, the capital city of West Java, as one of the most densely populated cities in Indonesia with a high HIV incidence, has yet to be conducted. The aim of this study was to analyze the impact of this triple elimination program in Bandung by assessing the data between 2017 and 2020. Monthly data was obtained from the Health Office of Bandung for four years, including number of screenings done for HIV, syphilis, and hepatitis B, number of confirmed cases and number of pregnant women treated for those infections. Additionally, data on children under 24 months old afflicted by these infections were also collected. Our data indicated an increase in screening coverage for HIV, syphilis, and HBV among pregnant women; however, it remained below the national set benchmarks for screening coverage. Only 59.5% of HIV-positive pregnant women received anti-retroviral therapy in 2020, while merely 25% of syphilis-positive cases were administered benzathine penicillin G. Syphilis screening was correlated with an increase in positive cases among children, suggesting missed opportunities in managing syphilis-positive pregnant women. Furthermore, management of HIV- and syphilis-positive cases had suboptimal outcomes. Data on hepatitis B was not evaluated since it was not available. To achieve the triple elimination program goals, comprehensive coordination among all relevant stakeholders is required, as is continuous monitoring and evaluation.

摘要

2018年,印度尼西亚政府启动了一项三重消除计划,以消除人类免疫缺陷病毒(HIV)、梅毒和乙型肝炎的母婴传播,旨在提高孕妇产前检查时的筛查接受率,并将这些感染在儿童中的发病率降低至每10万活产少于50例。尽管有这一举措,但尚未对其有效性进行全面评估,尤其是在西爪哇省省会万隆,作为印度尼西亚人口最密集且HIV发病率高的城市之一。本研究的目的是通过评估2017年至2020年的数据,分析该三重消除计划在万隆的影响。从万隆卫生局获取了四年的月度数据,包括HIV、梅毒和乙型肝炎的筛查次数、确诊病例数以及接受这些感染治疗的孕妇人数。此外,还收集了受这些感染影响的24个月以下儿童的数据。我们的数据表明,孕妇中HIV、梅毒和乙肝的筛查覆盖率有所提高;然而,仍低于国家设定的筛查覆盖率基准。2020年,只有59.5%的HIV阳性孕妇接受了抗逆转录病毒治疗,而梅毒阳性病例中只有25%接受了苄星青霉素G治疗。梅毒筛查与儿童阳性病例增加相关,表明在管理梅毒阳性孕妇方面存在错失的机会。此外,HIV和梅毒阳性病例的管理效果欠佳。由于没有可用数据,未对乙肝数据进行评估。为实现三重消除计划目标,所有相关利益攸关方需要进行全面协调,持续监测和评估也是如此。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7cdb/10919734/3a1be8b56933/NarraJ-3-e405-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7cdb/10919734/cc023e67471b/NarraJ-3-e405-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7cdb/10919734/210e11a12f34/NarraJ-3-e405-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7cdb/10919734/3a1be8b56933/NarraJ-3-e405-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7cdb/10919734/cc023e67471b/NarraJ-3-e405-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7cdb/10919734/210e11a12f34/NarraJ-3-e405-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7cdb/10919734/3a1be8b56933/NarraJ-3-e405-g003.jpg

相似文献

1
Evaluating the impact of triple elimination program for mother-to-child transmission of HIV, syphilis, and hepatitis B in Indonesia.评估印度尼西亚预防母婴传播艾滋病毒、梅毒和乙型肝炎三联消除计划的影响。
Narra J. 2023 Dec;3(3):e405. doi: 10.52225/narra.v3i3.405. Epub 2023 Nov 17.
2
Integrated approach for triple elimination of mother-to-child transmission of HIV, hepatitis B and syphilis is highly effective and cost-effective: an economic evaluation.综合方案消除艾滋病毒、乙肝和梅毒母婴传播效果显著且具有成本效益:经济评价。
Int J Epidemiol. 2019 Aug 1;48(4):1327-1339. doi: 10.1093/ije/dyz037.
3
Evaluation of Process Indicators and Challenges of the Elimination of Mother-to-Child Transmission of HIV, Syphilis, and Hepatitis B in Bali Province, Indonesia (2019-2022): A Mixed Methods Study.印度尼西亚巴厘省消除母婴传播艾滋病毒、梅毒和乙型肝炎的过程指标评估及挑战(2019 - 2022年):一项混合方法研究
Trop Med Infect Dis. 2023 Nov 3;8(11):492. doi: 10.3390/tropicalmed8110492.
4
Evaluating progress towards triple elimination of mother-to-child transmission of HIV, syphilis and hepatitis B in the Netherlands.评估荷兰在实现消除母婴传播艾滋病毒、梅毒和乙型肝炎方面的进展。
BMC Public Health. 2019 Mar 29;19(1):353. doi: 10.1186/s12889-019-6668-6.
5
Perspectives and challenges for mother-to-child transmission of HIV, hepatitis B, and syphilis in Brazil.巴西母婴传播艾滋病毒、乙型肝炎和梅毒的观点和挑战。
Front Public Health. 2023 Aug 8;11:1182386. doi: 10.3389/fpubh.2023.1182386. eCollection 2023.
6
Feasibility, benefits, and cost-effectiveness of adding universal hepatitis B and syphilis testing to routine antenatal care services in Thai Nguyen province, Vietnam.在越南太原省,将乙肝和梅毒普遍检测纳入常规产前护理服务的可行性、效益和成本效益。
Int J STD AIDS. 2021 Feb;32(2):135-143. doi: 10.1177/0956462420953722. Epub 2020 Dec 22.
7
Eliminating mother-to-child transmission of hepatitis B virus: practice and progress in Baoan, a national pilot district of China.消除乙型肝炎病毒母婴传播:中国宝安区国家级试点的实践与进展。
BMC Public Health. 2024 Jan 2;24(1):58. doi: 10.1186/s12889-023-17500-y.
8
[A study on the effectiveness of prevention of mother-to-child HIV, syphilis, and hepatitis B transmission among pregnant women in Dehong prefecture,Yunnan province, China from 2011 to 2013].[2011年至2013年中国云南省德宏州孕妇预防母婴传播艾滋病毒、梅毒和乙型肝炎有效性研究]
Zhonghua Yu Fang Yi Xue Za Zhi. 2014 Nov;48(11):942-6.
9
Prevalence of human immunodeficiency virus, syphilis, and hepatitis B and C virus infections in pregnant women: a systematic review and meta-analysis.孕妇人类免疫缺陷病毒、梅毒和乙型肝炎及丙型肝炎病毒感染的流行率:系统评价和荟萃分析。
Clin Microbiol Infect. 2023 Aug;29(8):1000-1007. doi: 10.1016/j.cmi.2023.03.002. Epub 2023 Mar 13.
10
Prevalence, seroconversion and mother-to-child transmission of dual and triplex infections of HIV, hepatitis B and C viruses among pregnant women in Nigeria: study protocol.尼日利亚孕妇中 HIV、乙型肝炎和丙型肝炎病毒双重和三重感染的流行率、血清转换率和母婴传播:研究方案。
Reprod Health. 2020 Sep 25;17(1):144. doi: 10.1186/s12978-020-00995-8.

引用本文的文献

1
Associations between socio-demographics, sexual knowledge and behaviour and sexually transmitted infections among reproductive-age women in Southeast Asia: Demographic Health Survey results.东南亚育龄妇女的社会人口统计学、性知识与行为和性传播感染之间的关联:人口与健康调查结果
BMC Public Health. 2025 Feb 22;25(1):738. doi: 10.1186/s12889-025-21962-7.

本文引用的文献

1
Global changes in maternity care provision during the COVID-19 pandemic: A systematic review and meta-analysis.新冠疫情期间全球孕产妇护理服务的变化:一项系统综述与荟萃分析。
EClinicalMedicine. 2021 Jun 19;37:100947. doi: 10.1016/j.eclinm.2021.100947. eCollection 2021 Jul.
2
Eliminating mother-to-child transmission of human immunodeficiency virus, syphilis and hepatitis B in sub-Saharan Africa.消除撒哈拉以南非洲的母婴传播艾滋病毒、梅毒和乙型肝炎。
Bull World Health Organ. 2021 Apr 1;99(4):287-295. doi: 10.2471/BLT.20.272559. Epub 2021 Jan 21.
3
Missed Opportunities for Prevention of Congenital Syphilis -United States, 2018.
2018年美国预防先天性梅毒的错失机遇
Pediatr Infect Dis J. 2020 Nov 1;39(11):1062. doi: 10.1097/INF.0000000000002833.
4
Feasibility, benefits, and cost-effectiveness of adding universal hepatitis B and syphilis testing to routine antenatal care services in Thai Nguyen province, Vietnam.在越南太原省,将乙肝和梅毒普遍检测纳入常规产前护理服务的可行性、效益和成本效益。
Int J STD AIDS. 2021 Feb;32(2):135-143. doi: 10.1177/0956462420953722. Epub 2020 Dec 22.
5
Early estimates of the indirect effects of the COVID-19 pandemic on maternal and child mortality in low-income and middle-income countries: a modelling study.对 COVID-19 大流行对低收入和中等收入国家母婴死亡率间接影响的早期估计:一项建模研究。
Lancet Glob Health. 2020 Jul;8(7):e901-e908. doi: 10.1016/S2214-109X(20)30229-1. Epub 2020 May 12.
6
Initiation of antiretroviral therapy or antiretroviral prophylaxis in pregnant women living with HIV registered in five townships of Mandalay, Myanmar: A cross sectional study.在缅甸曼德勒五个镇区登记的 HIV 阳性孕妇中启动抗逆转录病毒治疗或抗逆转录病毒预防:一项横断面研究。
BMC Pregnancy Childbirth. 2019 Dec 5;19(1):475. doi: 10.1186/s12884-019-2627-6.
7
Optimizing prevention of HIV mother to child transmission: Duration of antiretroviral therapy and viral suppression at delivery among pregnant Malawian women.优化艾滋病母婴传播预防:马拉维孕妇在分娩时抗逆转录病毒治疗和病毒抑制的持续时间。
PLoS One. 2018 Apr 3;13(4):e0195033. doi: 10.1371/journal.pone.0195033. eCollection 2018.
8
Shortages of benzathine penicillin for prevention of mother-to-child transmission of syphilis: An evaluation from multi-country surveys and stakeholder interviews.苄星青霉素预防梅毒母婴传播短缺:来自多国调查和利益攸关方访谈的评估。
PLoS Med. 2017 Dec 27;14(12):e1002473. doi: 10.1371/journal.pmed.1002473. eCollection 2017 Dec.
9
Three postpartum antiretroviral regimens to prevent intrapartum HIV infection.三种产后抗逆转录病毒方案预防围产期 HIV 感染。
N Engl J Med. 2012 Jun 21;366(25):2368-79. doi: 10.1056/NEJMoa1108275.