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接受血液透析的终末期肾脏病患者认知障碍的患病率及与其他因素的关系。

Prevalence of Cognitive Impairment and Relationships with Other Factors in Patients with End Stage Kidney Disease Receiving Hemodialysis.

机构信息

Was an Assistant Professor of Nursing, University of Virginia School of Nursing, Charlottesville, VA, at the time of this study.

Senior Clinical Research Coordinator, University of Virginia School of Nursing, Charlottesville, VA.

出版信息

Nephrol Nurs J. 2024 Jan-Feb;51(1):69-75.

PMID:38456729
Abstract

Despite recommendations, cognitive screening in patients with end stage kidney disease (ESKD) rarely happens, leading to underestimates of cognitive impairment (CI) prevalence and missed opportunities for intervention. We aimed to describe CI prevalence and associated factors in 100 patients receiving in-center hemodialysis aged 50 years and older. Cognitive function was measured using the Montreal Cognitive Assessment (MoCA). Descriptive analysis techniques characterized the sample and estimated mean scores. Non-parametric and parametric tests explored relationships among MoCA scores and other patient factors. Of the 100 patients, 32% had normal cognitive function, 56% mild CI, and 12% moderate CI. Age, income, and education level significantly corelated with cognitive function in our sample. Identifying clinical factors and appropriate follow up for abnormal screening are crucial next steps in managing cognitive impairment in patients with ESKD receiving in-center hemodialysis.

摘要

尽管有相关建议,但终末期肾病 (ESKD) 患者的认知筛查很少进行,导致认知障碍 (CI) 的患病率被低估,错失了干预的机会。我们旨在描述 100 名年龄在 50 岁及以上接受中心血液透析的患者的 CI 患病率和相关因素。认知功能使用蒙特利尔认知评估 (MoCA) 进行测量。描述性分析技术对样本进行了特征描述,并估计了平均分数。非参数和参数检验探讨了 MoCA 分数与其他患者因素之间的关系。在 100 名患者中,32%的患者认知功能正常,56%的患者轻度 CI,12%的患者中度 CI。在我们的样本中,年龄、收入和教育水平与认知功能显著相关。确定临床因素和异常筛查的适当随访是管理接受中心血液透析的 ESKD 患者认知障碍的下一步关键步骤。

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Altered interhemispheric functional connectivity in end-stage renal disease patients receiving hemodialysis without cognitive impairment.接受血液透析且无认知障碍的终末期肾病患者半球间功能连接改变。
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