Research Center for Emergency Medicine, Department of Clinical Medicine, Aarhus University, Aarhus, Denmark; Emergency Department, Horsens Regional Hospital, Horsens, Denmark.
Emergency Department, Aarhus University Hospital, Aarhus, Denmark.
Chest. 2024 Sep;166(3):544-560. doi: 10.1016/j.chest.2024.02.053. Epub 2024 Mar 7.
This scoping review was conducted to provide an overview of the evidence of point-of-care lung ultrasound (LUS) in emergency medicine. By emphasizing clinical topics, time trends, study designs, and the scope of the primary outcomes, a map is provided for physicians and researchers to guide their future initiatives.
Which study designs and primary outcomes are reported in published studies of LUS in emergency medicine?
We performed a systematic search in the PubMed/MEDLINE, Embase, Web of Science, Scopus, and Cochrane Library databases for LUS studies published prior to May 13, 2023. Study characteristics were synthesized quantitatively. The primary outcomes in all papers were categorized into the hierarchical Fryback and Thornbury levels.
A total of 4,076 papers were screened and, following selection and handsearching, 406 papers were included. The number of publications doubled from January 2020 to May 2023 (204 to 406 papers). The study designs were primarily observational (n = 375 [92%]), followed by randomized (n = 18 [4%]) and case series (n = 13 [3%]). The primary outcome measure concerned diagnostic accuracy in 319 papers (79%), diagnostic thinking in 32 (8%), therapeutic changes in 4 (1%), and patient outcomes in 14 (3%). No increase in the proportions of randomized controlled trials or the scope of primary outcome measures was observed with time. A freely available interactive database was created to enable readers to search for any given interest (https://public.tableau.com/app/profile/blinded/viz/LUSinEM_240216/INFO).
Observational diagnostic studies have been produced in abundance, leaving a paucity of research exploring clinical utility. Notably, research exploring whether LUS causes changes to clinical decisions is imperative prior to any further research being made into patient benefits.
本范围界定综述旨在提供有关急诊医学中即时肺部超声 (LUS) 证据的概述。通过强调临床主题、时间趋势、研究设计和主要结局的范围,为医生和研究人员提供了一张地图,以指导他们未来的计划。
发表的急诊医学中 LUS 研究报告了哪些研究设计和主要结局?
我们在 PubMed/MEDLINE、Embase、Web of Science、Scopus 和 Cochrane Library 数据库中进行了系统检索,检索截至 2023 年 5 月 13 日之前发表的 LUS 研究。综合了研究特征。所有论文的主要结局都分为 Fryback 和 Thornbury 层次结构的级别。
共筛选出 4076 篇论文,经过选择和手工检索,纳入了 406 篇论文。从 2020 年 1 月到 2023 年 5 月,出版物数量翻了一番(从 204 篇增加到 406 篇)。研究设计主要为观察性研究(n=375 [92%]),其次为随机对照试验(n=18 [4%])和病例系列研究(n=13 [3%])。主要结局指标在 319 篇论文(79%)中涉及诊断准确性,在 32 篇论文(8%)中涉及诊断思维,在 4 篇论文(1%)中涉及治疗变化,在 14 篇论文(3%)中涉及患者结局。随着时间的推移,随机对照试验的比例或主要结局测量范围没有增加。创建了一个免费的交互式数据库,使读者能够搜索任何给定的兴趣点(https://public.tableau.com/app/profile/blinded/viz/LUSinEM_240216/INFO)。
已经产生了大量的观察性诊断研究,而研究临床实用性的研究却很少。值得注意的是,在进一步研究患者获益之前,迫切需要研究 LUS 是否会导致临床决策的改变。