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新发脊髓损伤后疼痛与生活质量的相互关系。

Reciprocal association between pain and quality of life after newly acquired spinal cord injury.

机构信息

Department of Psychology, Pace University, 861 Bedford Rd, Pleasantville, NY, 10570, USA.

Swiss Paraplegic Research, Nottwil, Switzerland.

出版信息

Qual Life Res. 2024 May;33(5):1347-1357. doi: 10.1007/s11136-024-03615-1. Epub 2024 Mar 8.

Abstract

PURPOSE

Pain is highly prevalent in spinal cord injury (SCI) and a key determinant of quality of life (QoL). This is the first study to examine reciprocal associations between pain and QoL in patients undergoing their first inpatient rehabilitation after SCI.

METHODS

Longitudinal data, with three measurement time points (1 month and 3 months after SCI onset, and at discharge from inpatient rehabilitation) from the Inception Cohort of the Swiss Spinal Cord Injury Cohort Study. Participants were 381 individuals aged ≥ 16 years with a newly diagnosed traumatic or non-traumatic SCI. 75.1% were male and the average age was 53.2 years. Random intercept cross-lagged panel models were conducted to examine the reciprocal association between pain intensity and QoL, as measured with the International SCI QoL Basic Data Set three individual items (satisfaction with life, physical health, and psychological health) and total score (mean of the three individual items).

RESULTS

Both item and total QoL scores increased over time. 1 month: 5.3 (SD = 2.7), 3 months: 5.9 (SD = 2.3), discharge: 6.6 (SD = 2.0). Participants reported relatively low levels of pain intensity that remained stable over the course of inpatient rehabilitation. 1 month: 2.7 (SD = 2.3), 3 months: 2.6 (SD = 2.4), discharge: 2.7 (SD = 2.5). There were no significant cross-lagged associations between QoL and pain intensity across time.

CONCLUSION

Results indicate that pain intensity does not predict changes in QoL during first rehabilitation, and vice versa. Associations between pain intensity and QoL reported by previous studies may be attributable to individual characteristics and timely events that simultaneously influence pain and QoL.

摘要

目的

疼痛在脊髓损伤(SCI)中极为普遍,是生活质量(QoL)的关键决定因素。这是第一项研究,旨在检查 SCI 患者首次住院康复期间疼痛与 QoL 之间的相互关系。

方法

来自瑞士脊髓损伤队列研究的初始队列的纵向数据,有三个测量时间点(SCI 发病后 1 个月和 3 个月,以及住院康复出院时)。参与者为 381 名年龄≥16 岁的新发创伤性或非创伤性 SCI 患者。75.1%为男性,平均年龄为 53.2 岁。采用随机截距交叉滞后面板模型,使用国际 SCI QoL 基本数据集的三个个体项目(生活满意度、身体健康和心理健康)和总评分(三个个体项目的平均值)来评估疼痛强度和 QoL 之间的相互关系。

结果

个体项目和总 QoL 评分随时间增加而增加。1 个月:5.3(SD=2.7),3 个月:5.9(SD=2.3),出院时:6.6(SD=2.0)。参与者报告疼痛强度相对较低,在住院康复过程中保持稳定。1 个月:2.7(SD=2.3),3 个月:2.6(SD=2.4),出院时:2.7(SD=2.5)。在整个时间范围内,QoL 和疼痛强度之间没有显著的交叉滞后关联。

结论

结果表明,疼痛强度不能预测第一次康复期间 QoL 的变化,反之亦然。先前研究报告的疼痛强度与 QoL 之间的关联可能归因于同时影响疼痛和 QoL 的个体特征和及时事件。

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