Antibacterial prophylaxis for neutropenic and high-risk hematology patients-Do the benefits outweigh the risk?
作者信息
Reynolds Gemma, Lindsay Julian
机构信息
Department of Infectious Diseases, Peter MacCallum Cancer Centre, Melbourne, Victoria, Australia.
Sir Peter MacCallum Department of Oncology, University of Melbourne, Parkville, Victoria, Australia.
出版信息
Transpl Infect Dis. 2024 Apr;26(2):e14255. doi: 10.1111/tid.14255. Epub 2024 Mar 8.
Abstract
摘要
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Antibacterial prophylaxis for neutropenic and high-risk hematology patients-Do the benefits outweigh the risk?中性粒细胞减少和高危血液病患者的抗菌预防——益处是否大于风险？
Transpl Infect Dis. 2024 Apr;26(2):e14255. doi: 10.1111/tid.14255. Epub 2024 Mar 8.
2
Antibacterial prophylaxis in neutropenic patients.
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Counterpoint: routine anti-bacterial prophylaxis is not indicated in neutropenic patients with hematological malignancies.反驳观点：血液系统恶性肿瘤的中性粒细胞减少患者不建议进行常规抗菌预防。
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[Antibacterial Prophylaxis in Children and Adolescents Undergoing Therapy for Cancer - Statement of the Society of Pediatric Oncology and Hematology (GPOH) and of the German Society for Pediatric Infectious Diseases (DGPI) on Two Current International Guidelines].
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本文引用的文献
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The addition of doxycycline to fluoroquinolones for bacterial prophylaxis in autologous stem cell transplantation for multiple myeloma.在多发性骨髓瘤的自体干细胞移植中，氟喹诺酮类药物联合多西环素进行细菌预防。
Transpl Infect Dis. 2024 Apr;26(2):e14241. doi: 10.1111/tid.14241. Epub 2024 Jan 25.
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Gut microbiome correlates of response and toxicity following anti-CD19 CAR T cell therapy.抗 CD19 CAR T 细胞治疗后反应和毒性的肠道微生物组相关性。
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Clinical and microbiological impact of long-term discontinuation of fluoroquinolone prophylaxis in haematological patients with prolonged profound neutropenia.长期深度中性粒细胞减少症血液学患者停用氟喹诺酮预防用药的临床及微生物学影响
Eur J Haematol. 2021 Sep;107(3):377-379. doi: 10.1111/ejh.13670. Epub 2021 Jun 8.
4
Incidence of Febrile Neutropenia in Autologous Hematopoietic Stem Cell Transplant (HSCT) Recipients on levofloxacin prophylaxis.接受左氧氟沙星预防治疗的自体造血干细胞移植（HSCT）受者发热性中性粒细胞减少症的发生率。
Transpl Infect Dis. 2020 Apr;22(2):e13225. doi: 10.1111/tid.13225. Epub 2019 Dec 12.
5
Antimicrobial Stewardship in a Hematological Malignancy Unit: Carbapenem Reduction and Decreased Vancomycin-Resistant Enterococcus Infection.血液恶性肿瘤病房的抗菌药物管理：碳青霉烯类药物的减少和万古霉素耐药肠球菌感染的减少。
Clin Infect Dis. 2020 Aug 14;71(4):960-967. doi: 10.1093/cid/ciz900.
6
Levofloxacin prophylaxis in patients with newly diagnosed myeloma (TEAMM): a multicentre, double-blind, placebo-controlled, randomised, phase 3 trial.左氧氟沙星预防新诊断骨髓瘤患者（TEAMM）：一项多中心、双盲、安慰剂对照、随机、3 期临床试验。
Lancet Oncol. 2019 Dec;20(12):1760-1772. doi: 10.1016/S1470-2045(19)30506-6. Epub 2019 Oct 23.
7
Efficacy of antibiotic prophylaxis in patients with cancer and hematopoietic stem cell transplantation recipients: A systematic review of randomized trials.癌症和造血干细胞移植受者抗生素预防的疗效：随机试验的系统评价。
Cancer Med. 2019 Aug;8(10):4536-4546. doi: 10.1002/cam4.2395. Epub 2019 Jul 5.
8
Better Sepsis Management Rather Than Fluoroquinolone Prophylaxis for Patients With Cancer-Related Immunosuppression.对于癌症相关免疫抑制患者，优化脓毒症管理而非预防性使用氟喹诺酮类药物。
J Clin Oncol. 2019 May 1;37(13):1139-1140. doi: 10.1200/JCO.18.01474. Epub 2019 Mar 7.
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Antimicrobial Prophylaxis for Adult Patients With Cancer-Related Immunosuppression: ASCO and IDSA Clinical Practice Guideline Update.成人癌症相关免疫抑制患者的抗菌预防：ASCO 和 IDSA 临床实践指南更新。
J Clin Oncol. 2018 Oct 20;36(30):3043-3054. doi: 10.1200/JCO.18.00374. Epub 2018 Sep 4.
10
Fluoroquinolone prophylaxis reduces febrile neutropenia, bloodstream infections from mucosal translocations, and intensive care admissions in high risk hematological patients, a single center experience.
Leuk Lymphoma. 2019 Feb;60(2):488-492. doi: 10.1080/10428194.2018.1488252. Epub 2018 Aug 21.
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