Administration Department of Nosocomial Infection, State Key Laboratory of Oncology in South China, Guangdong Provincial Clinical Research Center for Cancer, Sun Yat-sen University Cancer Center, Guangzhou 510060, PR China.
Department of Medical Records and Statistics, State Key Laboratory of Oncology in South China, Guangdong Provincial Clinical Research Center for Cancer, Sun Yat-sen University Cancer Center, Guangzhou 510060, PR China.
Am J Infect Control. 2024 Aug;52(8):934-940. doi: 10.1016/j.ajic.2024.03.002. Epub 2024 Mar 7.
To evaluate the economic loss of hospital-acquired infections (HAIs) among tumor patients so as to help policymakers to allocate health care resources and address the issue.
We conducted a retrospective, 1:1 matched case-control study in a large region cancer hospital between January 1 and December 31, 2022. The economic burden was estimated as the median of the 1:1 pair differences of various hospitalization fees and hospital length of stay (LOS).
In this study of 329 matched pairs, the patients with HAIs incurred higher hospitalization cost (ie, $16,927) and experienced longer hospital LOS (ie, 22 days), compared to the non-HAI groups. The extra hospitalization cost and the prolonged hospital LOS caused by HAIs were $4,919 and 9 days, respectively. Accordingly, the direct nonmedical economic loss attributable to HAI was approximately $478 to 835 per case. Furthermore, the increment of hospitalization costs varied by sites of infection, types of tumors, and stratum of age.
HAIs lead to the increment of direct economic burden and hospital LOS in tumor patients. Our findings highlight the importance of implementing effective infection control measures in hospitals to reduce the financial burden on tumor patients.
评估肿瘤患者医院获得性感染（HAI）的经济损失，以帮助决策者分配卫生保健资源并解决这一问题。
我们在 2022 年 1 月 1 日至 12 月 31 日期间，在一家大型地区癌症医院进行了回顾性 1:1 病例对照研究。经济负担估计为各种住院费用和住院时间（LOS）的 1:1 对差的中位数。
在这项涉及 329 对匹配的研究中，与非 HAI 组相比，HAI 患者的住院费用更高（即 16927 美元），住院时间更长（即 22 天）。HAI 导致的额外住院费用和延长的住院时间分别为 4919 美元和 9 天。因此，HAI 导致的直接非医疗经济损失约为每个病例 478 至 835 美元。此外，住院费用的增加因感染部位、肿瘤类型和年龄层次而异。
HAI 导致肿瘤患者直接经济负担和住院时间的增加。我们的研究结果强调了在医院实施有效感染控制措施的重要性，以减轻肿瘤患者的经济负担。
