Department of Thoracic Surgery, The Second Xiangya Hospital of Central South University, Changsha, 410000, China.
Hunan Key Laboratory of Early Diagnosis and Precise Treatment of Lung Cancer, The Second Xiangya Hospital of Central South University, Changsha, China.
BMC Pediatr. 2024 Mar 9;24(1):173. doi: 10.1186/s12887-024-04615-3.
Pectus excavatum, the most common chest wall deformity, is frequently treated with Nuss procedure. Here we will describe non-invasive procedure and analyze the variables associated vacuum bell therapy for patients with pectus excavatum.
Retrospective case-control study in a single center between July 2018 and February 2022, including patients with pectus excavatum treated with vacuum bell. Follow-up was continued to September 2022. The Haller index and Correction index was calculated before and after treatment to analysis the effectiveness of vacuum bell therapy.
There were 98 patients enrolled in the treatment group, with 72 available for analysis, and the follow-up period ranged from 1.1 to 4.4 years (mean 3.3 years). When analyzing with the Haller Index, 18 patients (25.0%) showed excellent correction, 13 patients (18.1%) achieved good correction, and 4 patients (5.6%) had fair correction. The remaining patients had a poor outcome. Characteristics predicting a non-poor prognosis included initial age ≤ 11 years (OR = 3.94, p = 0.013) and patients with use over 24 consecutive months (OR = 3.95, p = 0.013). A total of 9 patients (12.5%) achieved a CI reduction below 10. Patients who started vacuum bell therapy at age > 11 had significantly less change compared to those who started at age ≤ 11 (P < 0.05). Complications included chest pain (5.6%), swollen skin (6.9%), chest tightness (1.4%) and erythema (15.3%).
A certain percentage of patients with pectus excavatum can achieve excellent correction when treated with pectus excavatum therapy. Variables predicting better outcome including initial age ≤ 11 years both in HI and CI and vacuum bell use over 24 consecutive months in HI. In summary, pectus excavatum is an emerging non-invasive therapy for pectus excavatum and will be widely performed in a certain group of patients.
漏斗胸是最常见的胸廓畸形,常采用 Nuss 手术治疗。在此,我们将描述一种非侵入性的方法,并分析真空钟治疗漏斗胸患者的相关变量。
回顾性单中心病例对照研究,纳入 2018 年 7 月至 2022 年 2 月期间采用真空钟治疗的漏斗胸患者。随访至 2022 年 9 月。治疗前后计算 Haller 指数和矫正指数,分析真空钟治疗的疗效。
共纳入 98 例患者纳入治疗组,其中 72 例可进行分析,随访时间为 1.1-4.4 年(平均 3.3 年)。采用 Haller 指数分析时,18 例(25.0%)患者矫正效果极佳,13 例(18.1%)患者矫正效果良好,4 例(5.6%)患者矫正效果尚可,其余患者矫正效果不佳。预测非不良预后的特征包括初始年龄≤11 岁(OR=3.94,p=0.013)和使用时间超过 24 个月(OR=3.95,p=0.013)。共有 9 例(12.5%)患者的 CI 降低低于 10。年龄>11 岁开始接受真空钟治疗的患者与≤11 岁开始治疗的患者相比,变化明显较小(P<0.05)。并发症包括胸痛(5.6%)、皮肤肿胀(6.9%)、胸闷(1.4%)和红斑(15.3%)。
采用漏斗胸治疗时,一定比例的漏斗胸患者可获得良好的矫正效果。预测治疗效果更好的变量包括初始年龄≤11 岁(无论是 HI 还是 CI),HI 中使用时间超过 24 个月。综上所述,漏斗胸是一种新兴的非侵入性治疗漏斗胸的方法,将在一定的患者群体中广泛开展。