Department of Thoracic and Cardiovascular Surgery, Korea University Anam Hospital, 73, Koryeodae-ro, Seongbuk-gu, Seoul, 02841, Republic of Korea.
Department of Biomedical Engineering, College of Software and Digital Healthcare Convergence, Yonsei University, Wonju, Republic of Korea.
Sci Rep. 2021 Nov 23;11(1):22787. doi: 10.1038/s41598-021-02250-x.
Vacuum bell therapy has been acceptable substitute for pectus excavatum patients who want to improve their appearance but avoid surgical correction. The aim of this study was to assess the pre-treatment characteristics of patients with pectus excavatum and to establish characteristics that can potentially help identify ideal candidates for vacuum bell therapy. Expected improvements in thoracic indices were evaluated using pre-treatment chest computed tomography, which was performed before and after applying a vacuum bell device. Treatment results after 1-year of application were evaluated using changes in the Haller index before and after treatment. The patients were categorized into two groups according the post- treatment changes in Haller index calculated using chest radiographs: those with changes in Haller index less than 0.5 (Group 1) and those with greater than or equal to 0.5 (Group 2). Pre-treatment Haller index was significantly lower in Group 1 than in Group 2 (3.1 ± 0.46 vs. 4.2 ± 1.14, respectively, p < 0.001). The expected improvement in Haller index in Group 2 was significantly higher than that in Group 1 (3.3 ± 0.60 vs. 2.8 ± 0.54, respectively, p = 0.001). The cut-off value of the expected improvement in Haller index was 0.46 with a sensitivity of 75.8% and a specificity of 83.3%. Patients who demonstrated pliability with a vacuum bell were identified as suitable candidates.
真空钟疗法已被接受为那些希望改善外观但避免手术矫正的漏斗胸患者的替代治疗方法。本研究旨在评估漏斗胸患者的治疗前特征,并确定可能有助于识别真空钟治疗理想人选的特征。使用治疗前胸部计算机断层扫描评估治疗前和应用真空钟装置后胸部指数的预期改善情况。使用治疗前后 Haller 指数的变化评估应用 1 年后的治疗结果。根据胸部 X 线片计算的治疗后 Haller 指数变化将患者分为两组:Haller 指数变化小于 0.5(组 1)和大于或等于 0.5(组 2)。组 1 的治疗前 Haller 指数明显低于组 2(分别为 3.1±0.46 和 4.2±1.14,p<0.001)。组 2 的 Haller 指数预期改善明显高于组 1(分别为 3.3±0.60 和 2.8±0.54,p=0.001)。Haller 指数预期改善的截止值为 0.46,其灵敏度为 75.8%,特异性为 83.3%。对真空钟具有柔韧性的患者被认为是合适的候选者。