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重大心胸外科手术中潜在侵袭性非结核分枝杆菌感染的风险。

Risk of Potential Invasive Non-Tuberculous Mycobacterial Infection in Major Cardiothoracic Surgeries.

机构信息

Department of Pathology, Peshawar Institute of Cardiology-MTI, Peshawar, Pakistan.

出版信息

J Coll Physicians Surg Pak. 2024 Mar;34(3):364-367. doi: 10.29271/jcpsp.2024.03.364.

DOI:10.29271/jcpsp.2024.03.364
PMID:38462877
Abstract

Nontuberculous Mycobacteria (NTM) commonly colonise municipal water supplies and cause healthcare-associated outbreaks. Although the infections are rare, they are associated with high mortality.  Aerosolization of NTM from colonised Heater cooler devices causes invasive infections in cardiac surgery patients. These units are widely used in open-chest heart surgery as an essential part of extracorporeal circulation but have been suggested as being a risk for infection.  Water disinfection as well as effective engineering-related mitigation strategies should be designed to decrease the burden of NTM in the hospital water supply. Key Words: Nontuberculous Mycobacteria, Heater cooler devices, Endocarditis, Water, Cardiothoracic surgeries.

摘要

非结核分枝杆菌(NTM)通常定植于市政供水系统,并引发与医疗保健相关的暴发。尽管这些感染较为罕见,但它们与高死亡率相关。NTM 从受污染的热交换器设备中气溶胶化,导致心脏外科手术患者发生侵袭性感染。这些装置在开胸心脏手术中被广泛用作体外循环的重要组成部分,但已被认为存在感染风险。应设计水消毒以及有效的工程相关缓解策略,以降低医院供水中 NTM 的负担。关键词:非结核分枝杆菌、热交换器设备、心内膜炎、水、心胸外科手术。

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