Shrestha Abhigan Babu, Gupta Pukar, Gurung Nisha, Kandel Sudarshan, Upadhyay Mahima, Gurung Amrita, Karki Shailendra, Mokbul Mobin Ibne
Department of Internal Medicine, M Abdur Rahim Medical College, Dinajpur.
Chitwan Medical College, Chitwan.
Ann Med Surg (Lond). 2024 Jan 11;86(3):1659-1663. doi: 10.1097/MS9.0000000000001698. eCollection 2024 Mar.
Herpes zoster (HZ) is a reactivation of the varicella-zoster virus (VZV) that can occur in people with weakened immune systems. Chronic obstructive pulmonary disease (COPD) is a chronic lung disease that can also impair the immune system.6-8.
The authors present the case of a 65-year-old male with COPD who developed HZ. The patient was initially admitted to the hospital for an acute exacerbation of COPD. After his condition stabilized, he developed vesicular rashes on the medial aspect of his left leg. A skin biopsy confirmed the diagnosis of HZ.
This case report provides further evidence that HZ can be induced in patients who are undergoing treatment for COPD. The authors recommend that COPD patients be vaccinated against HZ to prevent this complication.
HZ can develop in COPD patients, mainly using inhaled steroids. Compliance to medication should be monitored, on the other hand zoster vaccination should be provided to prevent it and its foremost complication which includes secondary bacterial infection, post-herpetic neuralgia, scarring, nerve palsy and encephalitis in case with disseminated zoster.
带状疱疹(HZ)是水痘-带状疱疹病毒(VZV)的再激活,可发生于免疫系统较弱的人群。慢性阻塞性肺疾病(COPD)是一种慢性肺部疾病,也会损害免疫系统。6-8。
作者报告了一例65岁患COPD的男性发生HZ的病例。该患者最初因COPD急性加重入院。病情稳定后,他左腿内侧出现水疱性皮疹。皮肤活检确诊为HZ。
本病例报告进一步证明,正在接受COPD治疗的患者可诱发HZ。作者建议COPD患者接种HZ疫苗以预防这种并发症。
COPD患者可发生HZ,主要是使用吸入性类固醇药物的患者。应监测药物依从性,另一方面应提供带状疱疹疫苗以预防HZ及其主要并发症,包括继发性细菌感染、带状疱疹后神经痛、瘢痕形成、神经麻痹以及播散性带状疱疹时的脑炎。