Vaez Mehrnaz, Sharifi Mehran, Karimi Sahar, Moghaddas Azadeh
Student of Pharmacy, Department of Clinical Pharmacy and Pharmacy Practice, Isfahan University of Medical Sciences, Isfahan, Iran.
Department of Internal Medicine, Isfahan University of Medical Sciences, Isfahan, Iran.
J Res Pharm Pract. 2024 Jan 31;12(2):33-43. doi: 10.4103/jrpp.jrpp_40_23. eCollection 2023 Apr-Jun.
This study aimed to comprehensively assess the challenges faced by a newly established clean room in the oncology center of Omid Hospital, Isfahan, Iran, one of the first of its kind in the country. The research also sought to identify the underlying causes of these challenges and propose potential solutions to address them.
A 6-month cross-sectional study was conducted from December 2021 to May 2022. International guidelines such as British Columbia Cancer Agencies' guideline of hazardous drugs, the National Institute for Occupational Safety and Health guideline for working with hazardous drugs, and United States pharmacopeia related to cleanroom performance were studied, translated, and summarized into a checklist. The staff performance in Omid Hospital's clean room was compared to the data collection form, and all medication errors were documented and analyzed. The study also explained the underlying causes of these challenges and proposed potential solutions.
Among 1005 chemotherapy regimens, 836 errors were detected, stemming from issues such as engineering and construction challenges, lack of human resources and essential equipment, and budgetary constraints.
Despite the involvement of a trained oncology clinical pharmacist, Omid Hospital's cleanroom faces significant challenges within the medical and hospital system, leading to non-standard challenges. The study recommends multidisciplinary approaches in the hospital to mitigate these challenges and improve cleanroom performance.
本研究旨在全面评估伊朗伊斯法罕奥米德医院肿瘤中心新建的洁净室所面临的挑战，该洁净室是该国首批此类洁净室之一。该研究还试图找出这些挑战的潜在原因，并提出应对这些挑战的潜在解决方案。
2021年12月至2022年5月进行了一项为期6个月的横断面研究。研究、翻译并总结了诸如不列颠哥伦比亚癌症机构的危险药物指南、美国国家职业安全与健康研究所的危险药物使用指南以及与洁净室性能相关的美国药典等国际指南，形成了一份检查表。将奥米德医院洁净室的工作人员表现与数据收集表进行比较，并记录和分析所有用药错误。该研究还解释了这些挑战的潜在原因，并提出了潜在解决方案。
在1005个化疗方案中，检测到836个错误，这些错误源于工程和建设挑战、人力资源和基本设备短缺以及预算限制等问题。
尽管有一名经过培训的肿瘤临床药剂师参与，但奥米德医院的洁净室在医疗和医院系统中仍面临重大挑战，导致出现不规范的情况。该研究建议医院采用多学科方法来缓解这些挑战并提高洁净室性能。
